【摘要】：目的探討免氣腹腹腔鏡膽道探查術(shù)對(duì)患者凝血功能的影響。方法選擇擇期行免氣腹腹腔鏡膽道探查術(shù)的26例患者,分別測(cè)定腹壁懸吊前、懸吊中、懸吊后及術(shù)后4組血漿樣本中組織因子活性(tissue factor activity,TF:A)、凝血酶-抗凝血酶Ⅲ復(fù)合物(thrombin-antithrombinⅢcomplexes,TAT)、血漿組織型纖溶酶原激活物(tissue-type plasminogen activator,t-PA)和纖溶酶原激活物抑制物(plasminogen activator inhibitor-1,PAI-1)的變化。結(jié)果 (1)TF:A值在4組中差異有統(tǒng)計(jì)學(xué)意義(P0.01),兩兩比較顯示,懸吊后與懸吊前、懸吊中、術(shù)后相比差異均有統(tǒng)計(jì)學(xué)意義(P0.01)。(2)TAT值在4組中差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。(3)t-PA值在4組中差異有統(tǒng)計(jì)學(xué)意義(P0.01),兩兩比較顯示,懸吊后與懸吊前、懸吊中相比差異有統(tǒng)計(jì)學(xué)意義(P0.01)。術(shù)后與懸吊前、懸吊中相比差異有統(tǒng)計(jì)學(xué)意義(P0.01)。(4)PAI值在4組中差異有統(tǒng)計(jì)學(xué)意義(P0.01),兩兩比較顯示,懸吊后與懸吊前、懸吊中、術(shù)后相比差異均有統(tǒng)計(jì)學(xué)意義(P0.01)。結(jié)論免氣腹腹腔鏡膽道探查術(shù)對(duì)患者凝血功能的影響處于機(jī)體自身可調(diào)節(jié)范圍內(nèi),術(shù)后早期無(wú)高凝狀態(tài)出現(xiàn)。
[Abstract]:Objective to investigate the effect of free pneumoperitoneum laparoscopic exploration of bile duct on coagulation function of patients. Methods Twenty six patients undergoing pneumoperitoneum laparoscopic choledochectomy were selected to measure the tissue factor activity (tissue factor activity,TF:A) in plasma samples before, during and after abdominal wall suspension, respectively. The changes of thrombin-antithrombin 鈪，

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