【摘要】：目的觀察利多卡因注射液聯(lián)合羅哌卡因注射液對斷指再植術(shù)的麻醉療效與安全性。方法將72例進(jìn)行斷指再植手術(shù)患者隨機(jī)分為對照組36例和試驗(yàn)組36例。對照組予以羅哌卡因注射液10 mL,上肢靜脈注射;試驗(yàn)組在對照組治療的基礎(chǔ)上,予以利多卡因注射液10 mL,上肢靜脈注射。比較2組患者的麻醉效果、C反應(yīng)蛋白(CRP)和藥物不良反應(yīng)的發(fā)生情況。結(jié)果試驗(yàn)組和對照組的麻醉效果Ⅰ級分別為97.22%(35/36例)和83.33%(30/36例),差異有統(tǒng)計(jì)學(xué)意義(P0.05)。術(shù)后1,3 d,試驗(yàn)組的CRP分別為(7.25±1.07),(7.14±0.96)mg·L~(-1),對照組的CRP分別為(8.12±1.18),(7.90±1.01)mg·L~(-1),差異均有統(tǒng)計(jì)學(xué)意義(均P0.05)。試驗(yàn)組的藥物不良反應(yīng)主要有肢動和皮膚潮紅,對照組的藥物不良反應(yīng)主要有肢動、皮膚潮紅和皮膚瘙癢。試驗(yàn)組和對照組的藥物不良反應(yīng)發(fā)生率分別為5.56%和22.22%,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論利多卡因注射液聯(lián)合羅哌卡因注射液對斷指再植術(shù)有較好的麻醉效果,且安全性較高。
[Abstract]:Objective to observe the anesthetic efficacy and safety of lidocaine injection combined with ropivacaine injection for replantation of severed fingers. Methods 72 patients were randomly divided into control group (n = 36) and experimental group (n = 36). The control group was treated with ropivacaine injection for 10 mL, and the experimental group with lidocaine injection for 10 mL,. The anaesthesia effects, C reactive protein (CRP) and adverse drug reactions were compared between the two groups. Results the anesthetic effects of the experimental group and the control group were 97.22% (35 / 36 cases) and 83.33% (30 / 36 cases) respectively. The difference was statistically significant (P0.05). The CRP of the trial group was (7.25 鹵1.07), (7.14 鹵0.96 mg L ~ (-1) on the 3rd day after operation, and the CRP of the control group was (8.12 鹵1.18), (7.90 鹵1.01 mg L ~ (-1), the difference was statistically significant (P0.05). The main adverse drug reactions in the test group were limb movement and flushing, while in the control group they were limb movement, flushing and pruritus. The incidence of adverse drug reactions in test group and control group were 5.56% and 22.22% respectively, the difference was statistically significant (P0.05). Conclusion Lidocaine injection combined with ropivacaine injection has better anaesthesia effect on replantation of severed fingers and has higher safety.
【作者單位】： 福建省立醫(yī)院麻醉科;福建中醫(yī)藥大學(xué)附屬第二人民醫(yī)院福建省第二人民醫(yī)院麻醉科;廣州醫(yī)科大學(xué)附屬樂從醫(yī)院麻醉科;
【基金】：佛山市醫(yī)學(xué)類科技攻關(guān)基金資助項(xiàng)目(20151021030016)
【分類號】：R614

【相似文獻(xiàn)】

相關(guān)期刊論文 前2條

1 袁蘇建;徐翔;黃曉菲;;2%利多卡因注射液牙槽神經(jīng)阻滯麻醉致不良反應(yīng)1例[J];藥物流行病學(xué)雜志;2012年04期

2 ;[J];;年期

，

本文編號：2279003