【摘要】：目的：系統(tǒng)評價胰腺中段切除術(shù)(CP)與胰腺體尾切除術(shù)(DP)的臨床療效。方法：應(yīng)用計算機檢索數(shù)據(jù)庫：中國知網(wǎng)CNKI旗下的相關(guān)期刊論文(1988.1-2014.3)；美國國立醫(yī)學(xué)圖書館(NLM)旗下的PubMed (1988.1～2014.3)、荷蘭醫(yī)學(xué)文摘數(shù)據(jù)庫EMBASE (1988.1～2014.3)、美國國立醫(yī)學(xué)圖書館MEDLINE (1988.1～2014.3)、美國科學(xué)引文索引SCI(1988.1～2014.3)和考克蘭圖書館The Cochrane Library(1988.1-2014.3),對照試驗中心注冊數(shù)據(jù)庫、學(xué)位論文數(shù)量庫和重要會議論文數(shù)據(jù)庫。對納入的15篇臨床對照試驗使用RevMa5.2軟件進行系統(tǒng)評價。結(jié)果：納入CP組(436例),DP組(643例),共1079例。Meta分析顯示,CP與DP相比,術(shù)后的胰瘺為38.3%(167/436)和24%(157/643),[OR：2.0,95%CI：1.48-2.71,0.01],CP組胰瘺發(fā)生率高,有統(tǒng)計學(xué)意義。術(shù)后并發(fā)癥率為45.7%(164/359)和31.7%(152/480),[OR：1.52,95%CI：1.11-2.08,0.05]。CP組并發(fā)癥發(fā)生率高,有統(tǒng)計學(xué)意義。內(nèi)分泌功能不足為5.9%(13/220)和24%(39/159),(OR：0.21,95%CI：0.06～0.78,P0.05)CP內(nèi)分泌發(fā)生率低,內(nèi)分泌不足有統(tǒng)計學(xué)意義；外分泌功能不足為7.1%(22/280)和9.1%(33/362),(OR：0.49,95%CI：0.27～0.78,P0.05),CP外分泌發(fā)生率低,外分泌不足有統(tǒng)計學(xué)意義。手術(shù)時間顯示兩組差異有統(tǒng)計學(xué)意義[SMD：59.23,95%CI：22.41～96.05,P0.01]。住院時間顯示兩組差異有統(tǒng)計學(xué)意義[SMD：7.01,95%CI：1.94～12.09,0.01]。結(jié)論胰腺中段切除雖然早期并發(fā)癥的發(fā)生率較高,但臨床上是可以接受的,胰腺中段切除可能是保留胰腺內(nèi)外分泌功能的合理手術(shù)方式。
[Abstract]:Objective: to evaluate the clinical effect of (CP) and (DP) in middle pancreatectomy. Methods: the full text database of Chinese periodicals (1988.1-2014.3) was searched by computer. PubMed (1988.1 / 2014.3), Netherlands Medical Abstract Database (EMBASE), MEDLINE (1988.1 / 2014.3), SCI (1988.1 / 2014.3) and The Cochrane Library (1988.1-2014.3, respectively. Academic dissertation database and important conference papers database. The 15 clinical controlled trials were systematically evaluated with RevMa5.2 software. Results: 1079 cases (1079 cases) were included in CP group. Meta-analysis showed that compared with DP, postoperative pancreatic fistula was 38.3% (167 / 436) and 24% (157 / 643). The incidence of pancreatic fistula in [OR:2.0,95%CI:1.48-2.71,0.01] CP group was higher than that in DP group. The rate of postoperative complications was 45.7% (164 / 359) and 31.7% (152 / 480) respectively. The incidence of complications in [OR:1.52,95%CI:1.11-2.08,0.05] .CP group was higher than that in control group (P < 0.05). The incidence of endocrine deficiency in CP was 5.9% (13 / 220) and 24% (39 / 159), (OR:0.21,95%CI:0.06~0.78,P0.05), and the incidence of endocrine deficiency was significantly lower than that in control group (7.1% (22 / 280) and 9.1% (33 / 362), (OR:0.49,95%CI:0.27~0.78,P0.05). The operative time was significantly different between the two groups [SMD:59.23,95%CI:22.41~96.05,P0.01]. The length of hospitalization was significantly different between the two groups [SMD:7.01,95%CI:1.94~12.09,0.01]. Conclusion although the incidence of early complications is high in the middle segment resection of pancreas, it is acceptable in clinic, and it may be a reasonable way to preserve the function of pancreatic exocrine and exocrine secretion.
【學(xué)位授予單位】：新疆醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2015
【分類號】：R657.5

【參考文獻】

相關(guān)期刊論文 前1條

1 萬濤;陳明易;周曉東;張安紅;賈偉;徐明月;馮玉泉;史憲杰;;中段胰腺切除術(shù)治療胰腺體部腫瘤的初步經(jīng)驗[J];中國現(xiàn)代醫(yī)學(xué)雜志;2013年14期

，

本文編號：2215192