創(chuàng)傷性骨折患者艱難梭狀芽孢桿菌感染的流行病學(xué)調(diào)查及對(duì)臨床預(yù)后的影響
[Abstract]:Objective to investigate the epidemiological investigation of Clostridium difficulty infection in patients with traumatic fracture and its influence on the clinical prognosis, so as to provide a reliable basis for the clinical prevention of Clostridium difficulty infection in patients with traumatic fracture. Methods 185 patients with traumatic open fracture complicated with diarrhea were selected from May 2012 to May 2016. 28 patients with Clostridium difficulty infection were selected as positive group. 60 patients without Clostridium challenge infection were selected as negative group, and the risk factors of Clostridium challenge infection were analyzed. The effect of Clostridium difficulty infection on serum inflammatory factor level, (ADL) score and hospitalization time of patients with ADL. Results out of 185 samples, 28 were positive for Clostridium diffcult toxin, the positive rate was 15.14.The single factor and multivariate logistic analysis showed that, The days of gastrointestinal diseases and diarrhea were independent risk factors of Clostridium difficulty infection in patients with traumatic open fracture. The serum levels of procalcitonin (PCT), interleukin-6 (IL-6) and hypersensitive C- reactive protein (hs-CRP) in patients with Clostridium challenge infection were significantly higher than those in the negative group. The difference was statistically significant (P0.05); the ADL score of the positive group was significantly lower than that of the negative group (P0.05). The hospitalization time of the positive group was significantly longer than that of the negative group (P0.05). Conclusion Gastrointestinal disease and long time diarrhea are independent risk factors of Clostridium difficulty infection in patients with traumatic open fracture. Clostridium difficulty infection will cause the increase of inflammatory level of patients and affect the prognosis of patients.
【作者單位】: 溫嶺市第一人民醫(yī)院骨科;溫嶺市第一人民醫(yī)院外科;溫嶺市第一人民醫(yī)院急診科;
【基金】:浙江省醫(yī)藥衛(wèi)生一般研究計(jì)劃基金資助項(xiàng)目(2015KYB448)
【分類號(hào)】:R683
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