本文選題：乳腺腫瘤 + 鉬靶X線攝影�。� 參考：《腫瘤》2017年11期

【摘要】：目的 :探討乳腺癌微鈣化征象與患者預(yù)后的相關(guān)性。方法 :將1 035例乳腺癌患者按術(shù)前鉬靶X線攝影檢查結(jié)果分成鈣化組和無(wú)鈣化組,分析鈣化與腫瘤大小、腋窩淋巴結(jié)狀態(tài)、組織學(xué)分級(jí),分子分型以及雌激素受體(estrogen receptor,ER)、孕激素受體(progesterone receptor,PR)和人表皮生長(zhǎng)因子受體2(human epidermal growth factor receptor-2,HER-2)之間的關(guān)系,評(píng)估微鈣化對(duì)預(yù)后的影響。結(jié)果:腋窩淋巴結(jié)轉(zhuǎn)移組患者的鈣化率[53.6%(199/371)]高于無(wú)淋巴結(jié)轉(zhuǎn)移組患者[47.1%(312/663)],HER-2陽(yáng)性組患者的鈣化率[63.3%(152/240)]高于陰性組患者[45.3%(360/795)],差異均有統(tǒng)計(jì)學(xué)意義(P值均0.05)。Luminal A型、Luminal B型、HER-2型和三陰型乳腺癌患者的鈣化率分別為39.4%(41/104)、49.3%(239/485)、68.3%(84/12)和38.8%(80/206),差異有統(tǒng)計(jì)學(xué)意義(P0.05)。鈣化組與無(wú)鈣化組的生存差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:乳腺癌鉬靶X線攝影檢查發(fā)現(xiàn)的鈣化征象與HER-2表達(dá)、分子分型和腋窩淋巴結(jié)狀態(tài)存在一定的相關(guān)性,鈣化對(duì)乳腺患者的生存無(wú)明顯影響。
[Abstract]:Objective: to investigate the correlation between microcalcification and prognosis of breast cancer. Methods: 1 035 patients with breast cancer were divided into calcified group and non calcified group according to the results of preoperative mammography. The size of tumor, axillary lymph node status and histological grade were analyzed. Molecular typing and the relationship between estrogen receptor ER, progesterone receptor PR and human epidermal growth factor receptor 2 (human epidermal growth factor receptor-2HER-2 were used to evaluate the effect of microcalcification on prognosis. Results: the calcification rate of patients with axillary lymph node metastasis [53.6% (199-371)] was higher than that of patients without lymph node metastasis [47.1% (312.1%)] HER-2 positive group [63.3% (152r240)] higher than that of negative group [45.3% (360-795)]. The difference was statistically significant (P = 0.05) .Luminal A Luminal B type HER-2 and Luminal A Luminal B type HER-2 and 鈪，

本文編號(hào)：2114742