本文選題：門(mén)脈高壓癥 + 脾切除術(shù)�。� 參考：《山西醫(yī)科大學(xué)》2015年碩士論文

【摘要】：目的:回顧性分析活血、抗凝藥物在門(mén)脈高壓癥脾切除術(shù)后預(yù)防門(mén)靜脈血栓形成的作用方法:回顧性收集山西醫(yī)科大學(xué)第一臨床醫(yī)學(xué)院及山西省人民醫(yī)院2009年9月—2014年9月收治的門(mén)靜脈高壓癥,并行脾切除術(shù)加賁門(mén)周?chē)茈x斷術(shù),根據(jù)術(shù)后是否應(yīng)用活血、抗凝藥物分為實(shí)驗(yàn)組27例(早期應(yīng)用活血、抗凝藥物),對(duì)照組33例(未應(yīng)用活血、抗凝藥物),觀(guān)察兩組在術(shù)后2個(gè)月內(nèi)凝血變化、肝功能的變化及門(mén)靜脈系統(tǒng)的血栓形成情況,比較兩組的性別、年齡、手術(shù)前和手術(shù)后各自的肝功能變化情況以及手術(shù)后發(fā)生門(mén)靜脈血栓的情況,同時(shí)采用統(tǒng)計(jì)學(xué)手段進(jìn)行分析。結(jié)果:對(duì)照組和實(shí)驗(yàn)組在一般情況(包括性別、年齡、脾臟大小、門(mén)靜脈及脾靜脈周徑)、發(fā)病原因、肝功能分級(jí)以及手術(shù)前后各項(xiàng)生化指標(biāo)無(wú)明顯差異(P0.05)。術(shù)后,對(duì)照組形成門(mén)靜脈血栓的發(fā)生率為33.3%,實(shí)驗(yàn)組形成門(mén)靜脈血栓的發(fā)生率為7.4%,兩者之間的差異具有顯著的統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:術(shù)后早期應(yīng)用活血、抗凝藥物可降低門(mén)脈高壓脾切除術(shù)后門(mén)靜脈血栓的發(fā)生,實(shí)驗(yàn)組未發(fā)生出血等情況,也未出現(xiàn)與使用活血、抗凝藥物有關(guān)的并發(fā)癥。
[Abstract]:Objective: to retrospectively analyze blood circulation, Effects of anticoagulants on prevention of portal vein thrombosis after splenectomy in patients with portal hypertension methods: the first Clinical College of Shanxi Medical University and the people's Hospital of Shanxi Province from September 2009 to September 2014 were collected retrospectively. Combined with splenectomy and pericardial devascularization, 27 cases of experimental group were divided into two groups according to whether or not to use blood circulation and anticoagulant drugs (early application of activating blood circulation, anticoagulant therapy) and control group of 33 cases (no application of activating blood circulation). Anticoagulant drugs were used to observe the changes of coagulation, liver function and thrombosis of portal vein system in the two groups within 2 months after operation, and to compare the sex and age of the two groups. The changes of liver function before and after operation and portal vein thrombosis after operation were analyzed statistically. Results: there were no significant differences between the control group and the experimental group (including sex, age, spleen size, portal vein and splenic vein diameter, the cause of the disease, liver function grading and biochemical indexes before and after operation). After operation, the incidence of portal vein thrombosis in the control group was 33.3%, and that in the experimental group was 7.4%. The difference between the two groups was statistically significant (P 0.05). Conclusion: the early application of blood circulation and anticoagulant drugs can reduce the occurrence of venous thrombosis in the back door of portal hypertension splenectomy, and there is no bleeding in the experimental group, and there are no complications related to the use of blood circulation and anticoagulant drugs.
【學(xué)位授予單位】：山西醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2015
【分類(lèi)號(hào)】：R657.6

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