本文選題：低強(qiáng)度脈沖超聲波 + 創(chuàng)傷性膝關(guān)節(jié)骨性關(guān)節(jié)炎�。� 參考：《中國康復(fù)醫(yī)學(xué)雜志》2016年08期

【摘要】：目的:觀察低強(qiáng)度脈沖超聲(low intensity pulsed ultrasound,LIPUS)聯(lián)合藥物治療對創(chuàng)傷性膝關(guān)節(jié)骨性關(guān)節(jié)炎(traumatic knee osteoarthritis,TKOA)的臨床治療效果。方法:將60例TKOA患者隨機(jī)分為聯(lián)合組、對照1組和對照2組,20例/組。聯(lián)合組:予LIPUS聯(lián)合口服非甾體類抗炎藥(NSAIDs)治療;對照1組:予單純LIPUS治療;對照2組:予單純口服NSAIDs治療。分別在治療前后,進(jìn)行3組間的VAS評分、(Western Ontario and Mc Master universities osteoarthritis index,WOMAC)評分、(Lysholm knee score,LKSS)評分;并經(jīng)MRI檢查行ICRS標(biāo)準(zhǔn)分級,測量膝關(guān)節(jié)內(nèi)外側(cè)髁、髕軟骨外側(cè)、內(nèi)側(cè)軟骨T2值。結(jié)果:經(jīng)6周治療后,三組VAS評分、WOMAC評分、LKSS評分均較治療前有不同程度的改善,聯(lián)合組療效明顯優(yōu)于對照1組(P0.05)和對照2組(P0.05),對照1組優(yōu)于對照2組,但無顯著性意義(P0.05);三組MRI檢查T2值結(jié)果無論與檢查前比較,還是三組間比較均未見明顯治療效果(P0.05)。結(jié)論:LIPUS聯(lián)合藥物治療可改善TKOA患者的臨床癥狀和/或體征,可一定程度的提高患者的膝關(guān)節(jié)功能,但對依據(jù)MRI檢查的TKOA患者膝關(guān)節(jié)軟骨的損害或退變程度無明顯關(guān)聯(lián)性。
[Abstract]:Objective: to observe the clinical effect of low intensity pulsed ultrasound (LIPUS) combined with medicine on traumatic knee osteoarthritis (TKOAA). Methods: 60 patients with TKOA were randomly divided into two groups: control group (n = 20), control group (n = 20) and control group (n = 20). The combined group was treated with LIPUS combined with oral NSAIDs, the control group was treated with LIPUS alone and the control group with oral NSAIDs. Before and after treatment, the three groups were divided into three groups: Western and Mc master universities osteoarthritis index and WOMAC) scores, and MRI examination was performed to measure the T _ 2 values of the medial and lateral condyle, lateral patellar cartilage and medial articular cartilage. Results: after 6 weeks of treatment, the VAS score and WOMAC score and LKSS score of the three groups were improved to some extent, and the curative effect of the combined group was significantly better than that of the control group 1 (P 0.05) and the control group 2 (P 0.05), the control group 1 was superior to the control group 2 (P 0.05), and the control group 1 was superior to the control group 2. However, there was no significant difference between the three groups in terms of the T _ 2 value of MRI, and no significant therapeutic effect was found in the three groups either before or between the three groups. Conclusion the clinical symptoms and / or signs of TKOA patients can be improved by using the combined drug therapy of TKOA, and the knee joint function can be improved to some extent, but there is no significant correlation between the damage or degeneration degree of articular cartilage in TKOA patients based on MRI.
【作者單位】： 南京醫(yī)科大學(xué)附屬南京醫(yī)院(南京市第一醫(yī)院)康復(fù)醫(yī)學(xué)科;
【基金】：南京市醫(yī)學(xué)科技發(fā)展基金項(xiàng)目(YKK13113)
【分類號】：R684.3

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