本文選題：重型顱腦損傷 + 肺部感染��； 參考：《基因組學(xué)與應(yīng)用生物學(xué)》2016年11期

【摘要】：探討重型顱腦損傷監(jiān)測降鈣素原和超敏C反應(yīng)蛋白對感染的鑒別診斷應(yīng)用。選擇我院2015年1月至2016年1月所接診的80例重型顱腦損傷患者,其中40例伴有肺部感染作為感染組,其余40例為未感染組,在感染當(dāng)天檢測降鈣素原(PCT)、超敏C反應(yīng)蛋白(hs-CRP)水平,感染組患者給予相應(yīng)的抗感染治療后,根據(jù)患者感染情況進(jìn)行分組,在感染后3 d、感染后7 d時分別對PCT、hs-CRP水平進(jìn)行檢測。在感染當(dāng)天,感染組PCT、hs-CRP水平均比未感染組高((3.85±0.51)ng/m L比(0.53±0.15)ng/m L,(61.23±17.34)mg/L比(50.12±13.12)mg/L)(p0.05);在感染組患者中,24例患者感染好轉(zhuǎn),感染后3 d、感染后7 d時,PCT、hs-CRP水平均比確認(rèn)感染當(dāng)天得到降低(p0.05);另外16例患者感染持續(xù),在感染后3 d、感染后7 d時,PCT、hs-CRP水平均發(fā)生持續(xù)性升高,與確認(rèn)感染當(dāng)天比較差異具有統(tǒng)計學(xué)意義(p0.05)。PCT和hs-CRP的檢測在重型顱腦損傷并發(fā)肺部感染患者中具有較高的特異性敏感性,有利于臨床評估。
[Abstract]:To investigate the application of monitoring procalcitonin and hypersensitive C reactive protein in the differential diagnosis of severe craniocerebral injury. From January 2015 to January 2016, 80 patients with severe craniocerebral injury were selected, including 40 patients with pulmonary infection and 40 patients with no infection. The levels of procalcitonin protopril (PCT) and hypersensitive C-reactive protein (hs-CRP) were measured on the day of infection. The patients in the infection group were divided into groups according to the infection status after the corresponding anti-infection treatment. The levels of PCThs-CRP were detected at 3 days after infection and 7 days after infection. On the day of infection, the levels of hs-CRP in the infected group were higher than those in the non-infected group (3.85 鹵0.51)ng/m L vs 0.53 鹵0.15)ng/m L, 61.23 鹵17.34)mg/L vs 50.12 鹵13.12 mg / L, respectively). The levels of PCThs-CRP at 3 days after infection and 7 days after infection were lower than those on the day of confirmed infection, and the levels of PCThs-CRP in 16 other patients continued to increase at 3 days after infection and 7 days after infection. Compared with the confirmed infection day, the detection of p0.05, PCT and hs-CRP in patients with severe craniocerebral injury complicated with pulmonary infection has a high specificity and sensitivity, which is helpful for clinical evaluation.
【作者單位】： 西南醫(yī)科大學(xué)附屬醫(yī)院神經(jīng)外科;內(nèi)江市第一人民醫(yī)院神經(jīng)外科;
【分類號】：R651.15

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本文編號：1981119