發(fā)布時間：2018-06-02 13:52

  本文選題：膝關(guān)節(jié) + 類風(fēng)濕關(guān)節(jié)炎��； 參考：《基因組學(xué)與應(yīng)用生物學(xué)》2017年04期

【摘要】：為了系統(tǒng)的評估膝關(guān)節(jié)類風(fēng)濕性關(guān)節(jié)炎關(guān)節(jié)鏡滑膜切除術(shù)后影響疼痛的因素和解決方法,本研究利用VAS和KSS系統(tǒng)評估了所在醫(yī)院自2011年1月至2015年1月間57例膝關(guān)節(jié)類風(fēng)濕關(guān)節(jié)炎行關(guān)節(jié)鏡下滑膜切除術(shù)患者,我們將術(shù)后31例患者給予抗類風(fēng)濕藥物治療6~12個月設(shè)為A組,26例病例未進行抗類風(fēng)濕藥物治療或拒絕藥物治療的設(shè)為B組。術(shù)后3個月和6個月來院復(fù)查檢測類風(fēng)濕因子、血沉、C反應(yīng)蛋白指標(biāo),疼痛模擬視覺評分(VAS)評分評估疼痛情況,膝關(guān)節(jié)功能KSS評分評估關(guān)節(jié)功能。所有患者進行多因素Logistic回歸分析術(shù)后疼痛緩解因素,57例患者均獲得術(shù)后6~18個月隨訪。研究結(jié)果表明,術(shù)后6個月膝前痛緩解率為73.7%(42/57),疼痛模擬視覺評分(VAS)平均(3.3±1.1)分;給予抗類風(fēng)濕藥物治療的患者術(shù)后疼痛緩解率(80.6%,25/31)明顯高于未給予藥物治療的患者(65.4%,17/26);單因素分析顯示不同性別、年齡、手術(shù)時間等因素下患者行術(shù)后膝前痛的發(fā)生率差異無顯著性(p0.05),多因素Logistic回歸分析結(jié)果顯示患者合并抗類風(fēng)濕藥物治療是緩解膝關(guān)節(jié)類風(fēng)濕關(guān)節(jié)炎關(guān)節(jié)鏡滑膜切除術(shù)后膝前痛的獨立影響因素(p0.05)。我們的評估分析初步表明:膝關(guān)節(jié)類風(fēng)濕性關(guān)節(jié)炎患者行關(guān)節(jié)鏡下滑膜切除術(shù)后發(fā)生膝前痛緩解率與術(shù)后合并抗類風(fēng)濕藥物有關(guān),與患者年齡、性別、手術(shù)時間等無關(guān)。
[Abstract]:In order to systematically evaluate the factors affecting the pain after arthroscopic synovectomy for rheumatoid arthritis of the knee, In this study, 57 patients with rheumatoid arthritis of the knee underwent arthroscopic synovectomy in our hospital from January 2011 to January 2015, using VAS and KSS systems. Thirty-one patients were treated with antirheumatoid drugs for 6 ~ 12 months after operation. Group A was divided into group A (n = 26) and group B (without or without antirheumatoid drug therapy). Rheumatoid factor, erythrocyte sedimentation rate C reactive protein (ESR), visual analogue pain score (VASS) and knee joint function (KSS) were measured 3 months and 6 months after operation. All patients were followed up for 6 ~ 18 months by multivariate Logistic regression analysis. The results showed that the relief rate of anterior knee pain was 73.7 / 57 / 57.The average score of visual analogue pain score (VASs) was 3.3 鹵1.1). The postoperative pain relief rate of patients who were treated with antirheumatoid drugs was significantly higher than that of patients who had not been treated with antirheumatoid drugs (80.6 or 25 / 31). Univariate analysis showed that there were different genders and ages. There was no significant difference in the incidence of postoperative anterior knee pain between the patients with operative time and other factors. The results of multivariate Logistic regression analysis showed that the combination of anti-rheumatoid drugs was the relief of arthroscopic synovectomy in patients with rheumatoid arthritis of the knee. The independent influencing factors of anterior knee pain after operation were p0.05. Our evaluation and analysis showed that the relief rate of anterior knee pain after arthroscopic synovectomy was related to postoperative antirheumatoid drugs, but it was not related to age, sex and operation time of patients with rheumatoid arthritis.
【作者單位】： 江漢大學(xué)附屬醫(yī)院;湖北醫(yī)藥學(xué)院附屬太和醫(yī)院;
【基金】：江漢大學(xué)附屬醫(yī)院 湖北醫(yī)藥學(xué)院附屬太和醫(yī)院資助
【分類號】：R687.4
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本文編號：1968996