本文選題：微生態(tài)制劑 + 炎性腸梗阻��； 參考：《蘭州大學(xué)》2017年碩士論文

【摘要】：目的探究微生態(tài)制劑輔助治療術(shù)后早期炎性腸梗阻的臨床療效,并再次認(rèn)識(shí)EPII的臨床特點(diǎn)。方法回顧性分析蘭州大學(xué)第一醫(yī)院2012年1月至2016年6月收治的70例術(shù)后早期炎性腸梗阻患者的基本資料,根據(jù)在常規(guī)治療的基礎(chǔ)上是否應(yīng)用消化道微生態(tài)制劑分為對(duì)照組(31例)和干預(yù)組(39例)。收集整理兩組患者臨床資料及隨訪數(shù)據(jù),總結(jié)EPII的臨床特點(diǎn),采用SPSS 22.0統(tǒng)計(jì)學(xué)軟件分析兩組患者臨床療效及外周血PCT、淋巴細(xì)胞計(jì)數(shù)的變化。結(jié)果1、70例患者均保守治愈出院,其中1例發(fā)生應(yīng)激性消化道出血,予以保守治療后治愈出院。2、術(shù)后早期炎性腸梗阻多發(fā)生于腸道手術(shù)后,保守治療多有效。3、干預(yù)組腹脹消失時(shí)間[(2.38±0.59)天]、腸鳴音恢復(fù)時(shí)間[(5.74±2.91)天]、肛門排氣時(shí)間[(7.08±3.52)天]和住院時(shí)間[(9.44±3.91)天]均較對(duì)照組[(2.74±0.51)天]、[(7.84±3.66)天]、[(9.74±4.45)天]、[(12.29±4.91)天]縮短,兩組差異有統(tǒng)計(jì)學(xué)意義(P0.05)。4、兩組患者經(jīng)治療血清降鈣素原均下降,淋巴細(xì)胞絕對(duì)值均增加,其變化差異有統(tǒng)計(jì)學(xué)意義(P0.05)。5、70例患者出院后隨訪3~9個(gè)月,失訪6例(8.57%),收集到隨訪資料的64例患者中復(fù)發(fā)腸梗阻4例(6.25%),無1例手術(shù),僅1例因腸梗阻較重住院保守治療。結(jié)論對(duì)于診斷明確的術(shù)后早期炎性腸梗阻患者,采用保守治療的方法多有效;微生態(tài)制劑用于術(shù)后早期炎性腸梗阻的治療可縮短治療時(shí)間,促進(jìn)腸道免疫功能恢復(fù),且使用安全,值得臨床推廣。
[Abstract]:Objective to explore the clinical effect of microecological preparation in the treatment of early postoperative inflammatory intestinal obstruction and to recognize the clinical characteristics of EPII. Methods the data of 70 patients with early postoperative inflammatory intestinal obstruction treated in the first Hospital of Lanzhou University from January 2012 to June 2016 were retrospectively analyzed. On the basis of routine treatment, the patients were divided into control group (n = 31) and intervention group (n = 39). The clinical data and follow-up data of the two groups were collected, and the clinical characteristics of EPII were summarized. The clinical efficacy, peripheral blood PCT and lymphocyte count of the two groups were analyzed by SPSS 22.0 software. Results (1) 70 patients were cured and discharged, one of them suffered from stress gastrointestinal hemorrhage and was cured after conservative treatment. The early postoperative inflammatory intestinal obstruction occurred mostly after intestinal operation. The duration of abdominal distension disappeared [2.38 鹵0.59) days, the recovery time of bowel sounds [5.74 鹵2.91] days, the time of anal exhaust [7.08 鹵3.52) days] and the hospitalization time [9.44 鹵3.91 days] in the intervention group were shorter than those in the control group [2.74 鹵0.51) days, [7.84 鹵3.66) days], [9.74 鹵4.45) days], [12.29 鹵4.91) days]. The difference between the two groups was statistically significant (P 0.05N. 4). The serum procalcitonin level decreased and the absolute value of lymphocyte increased in the two groups. The difference was statistically significant in 70 patients with P0.05An. 5The follow-up period was 3 ~ 9 months after discharge. Among 64 patients with recurrent intestinal obstruction, 4 cases had recurrent intestinal obstruction, none had surgery, and only 1 case was treated conservatively because of severe intestinal obstruction. Conclusion the conservative treatment is more effective for the patients with early postoperative inflammatory intestinal obstruction, and the treatment of early postoperative inflammatory intestinal obstruction with microecological preparation can shorten the treatment time and promote the recovery of intestinal immune function. It is safe to use and is worth popularizing in clinic.
【學(xué)位授予單位】：蘭州大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R656.7

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本文編號(hào)：1944994