膝關(guān)節(jié)鏡術(shù)后關(guān)節(jié)腔注射不同濃度右美托咪定復(fù)合羅哌卡因的鎮(zhèn)痛效果
發(fā)布時間:2018-05-26 18:32
本文選題:右美托咪定 + 羅哌卡因; 參考:《中國老年學(xué)雜志》2017年08期
【摘要】:目的觀察關(guān)節(jié)腔內(nèi)注射右美托咪定復(fù)合羅哌卡因?qū)οリP(guān)節(jié)鏡術(shù)后鎮(zhèn)痛的效果。方法 60例擇期膝關(guān)節(jié)鏡手術(shù)患者隨機分為A、B、C 3組,術(shù)畢A組關(guān)節(jié)腔內(nèi)注射0.25%羅哌卡因20 ml,B組關(guān)節(jié)腔內(nèi)注射0.25%羅哌卡因+0.5μg/kg右美托咪定20 ml,C組0.25%羅哌卡因+1μg/kg右美托咪定20 ml,視覺模擬評分(VAS)≥4分時肌注芬太尼鎮(zhèn)痛,鎮(zhèn)痛效果根據(jù)VAS、鎮(zhèn)痛持續(xù)時間和術(shù)后24 h內(nèi)芬太尼用量評估。結(jié)果術(shù)后B、C組VAS及芬太尼用量顯著低于A組,C組VAS及芬太尼用量顯著低于B組(P0.05)。B、C組術(shù)后鎮(zhèn)痛持續(xù)時間顯著長于A組,C組術(shù)后鎮(zhèn)痛持續(xù)時間顯著長于B組(P0.05)。結(jié)論關(guān)節(jié)腔內(nèi)注射右美托咪定可明顯增強羅哌卡因用于膝關(guān)節(jié)鏡術(shù)后鎮(zhèn)痛的效果,且其鎮(zhèn)痛效果呈濃度依賴性。
[Abstract]:Objective to observe the effect of intraarticular injection of dexmetidine combined with ropivacaine on postoperative analgesia of knee arthroscopy. Methods Sixty patients undergoing selective arthroscopic knee arthroscopy were randomly divided into three groups: group A and group C, At the end of operation, 0.25% ropivacaine was injected into the articular cavity of group A and 0.25% ropivacaine was injected into the articular cavity of group B with 0.25% ropivacaine 0.5 渭 g/kg and dexmetomidine 20 ml. Group C received intramuscular injection of fentanyl when the score of visual analogue score (VAS) was 鈮,
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