本文選題：C-反應(yīng)蛋白 + 普外科��； 參考：《中華醫(yī)院感染學(xué)雜志》2017年11期

【摘要】：目的探討C-反應(yīng)蛋白(CRP)對普外科患者手術(shù)后腹腔感染性并發(fā)癥的預(yù)測效果,為臨床預(yù)防治療提供參考。方法回顧性分析醫(yī)院2010年1月-2015年12月1 200例普外科手術(shù)患者病歷資料,根據(jù)是否發(fā)生腹腔感染性并發(fā)癥將患者分為感染組(腹腔感染)和未感染組,按照傾向性評分匹配法,將腹腔感染性并發(fā)癥患者∶無感染患者=1∶2的比例篩選一般資料無差異的患者,符合納入標(biāo)準(zhǔn)的患者642例,其中感染組患者214例,未感染組患者428例,統(tǒng)計兩組患者的年齡、手術(shù)史、手術(shù)時間、術(shù)中出血量、術(shù)中輸血等,采用免疫比濁法檢測所有患者手術(shù)前后CRP水平,對感染組患者的痰、分泌物、穿刺液及尿、血等進(jìn)行細(xì)菌培養(yǎng)和鑒定。結(jié)果 214例腹腔感染患者中共檢測出病原菌253株,其中革蘭陰性菌205株占81.03%,以肺炎克雷伯菌和大腸埃希菌所占比例最高,革蘭陽性菌48株占18.97%,以金黃色葡萄球菌所占比例最高,感染組和未感染組患者術(shù)后1d、3d中性粒細(xì)胞百分比和白細(xì)胞計數(shù)比較差異無統(tǒng)計學(xué)意義,但感染組患者CRP水平顯著高于對照組,差異有統(tǒng)計學(xué)意義(P0.05)。結(jié)論 CRP對普外科患者手術(shù)后腹腔感染性并發(fā)癥具有較好的預(yù)測效果與臨床應(yīng)用價值。
[Abstract]:Objective to investigate the predictive effect of C-reactive protein (CRP) on postoperative abdominal infectious complications in patients undergoing general surgery, and to provide reference for clinical prevention and treatment. Methods the medical records of 1,200 patients undergoing general surgery from January 2010 to December 2015 in our hospital were retrospectively analyzed. The patients were divided into infected group (abdominal infection) and non-infected group according to the incidence of intraperitoneal infectious complications. According to the tendency score matching method, the patients were divided into two groups. 642 patients with intraperitoneal infectious complications, including 214 patients in infection group and 428 patients in uninfected group, were selected by the ratio of 1: 2 to 1: 2. The age of the patients in the two groups was counted as follows: there were 642 patients who met the inclusion criteria, including 214 patients in the infection group, 428 patients in the uninfected group, and the age of the patients in the two groups. History of operation, time of operation, amount of intraoperative blood loss, intraoperative blood transfusion and so on. The levels of CRP in all patients before and after operation were detected by immunoturbidimetry. The sputum, secretion, puncture fluid, urine and blood of infected patients were cultured and identified. Results 253 strains of pathogenic bacteria were detected in 214 patients with intraperitoneal infection. Among them, 205 strains of Gram-negative bacteria accounted for 81.03 strains, among which Klebsiella pneumoniae and Escherichia coli accounted for the highest proportion, 48 strains of Gram-positive bacteria accounted for 18.97 strains, and Staphylococcus aureus accounted for the highest proportion. There was no significant difference in neutrophil percentage and leukocyte count between the infected group and the uninfected group on the 1st day after operation, but the CRP level in the infected group was significantly higher than that in the control group (P 0.05). Conclusion CRP has a good predictive effect and clinical application value for postoperative abdominal infectious complications in patients with general surgery.
【作者單位】： 紹興市中心醫(yī)院普外科;
【分類號】：R619.3

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