本文選題：低強度脈沖超聲 + 骨腱連接點　； 參考：《中國康復醫(yī)學雜志》2017年02期

【摘要】：目的:觀察低強度脈沖超聲(LIPUS)治療骨-腱連接點(bone-tendon junction,BTJ)損傷的效果,及對骨血管重建相關因子的促進作用。方法:選取BTJ損傷患者41例,采用LIPUS治療2周。采用放射免疫法和酶聯(lián)吸附免疫法(ELISA)檢測堿性成纖維細胞生長因子(bFGF)、血小板衍生因子(PDGF)、血管內(nèi)皮生長因子(VEGF)、轉化生長因子-β(TGF-β)及基質金屬蛋白酶-3(MMP-3)。采用疼痛視覺模擬評分(VAS)及功能指標變化,評價LIPUS的治療效果。結果:經(jīng)LIPUS治療2周后,血清中bFGF、PDGF、VEGF、TGF-β及MMP-3水平較治療前均明顯升高(P0.05或P0.01);VAS評分較治療前明顯下降([7.42±1.89)vs(4.00±1.05)分,t=8.492,P=0.000],Lysholm膝關節(jié)功能評分[(65.74±4.05)vs(83.69±8.25)分,t=5.114,P=0.000]、每分鐘上下臺階次數(shù)([24.81±5.19)vs(40.32±6.33)次/min,t=15.333,P=0.000]及每日平均運動時間([20.25±2.74)vs(72.30±8.52)min/d,t=14.305,P=0.000]均較治療前明顯升高(P=0.000)。每日平均運動時間隨時間呈逐漸增高趨勢,由72h開始,與治療前比較,差異有顯著性意義(P0.01)。結論:LIPUS治療可提高骨血管重建相關因子水平,促進BTJ損傷恢復,效果顯著。
[Abstract]:Objective: to observe the effect of low intensity pulsed ultrasound (LIPUSS) on the injury of bone-tendon junctional joint (BTJ) and the factors related to bone vascular remodeling. Methods: 41 patients with BTJ injury were treated with LIPUS for 2 weeks. Radioimmunoassay (RIA) and enzyme linked immunosorbent assay (Elisa) were used to detect basic fibroblast growth factor (bFGFN), platelet-derived factor (PDGF), vascular endothelial growth factor (VEGF), transforming growth factor- 尾 (TGF- 尾) and matrix metalloproteinase-3 (MMP-3). The effect of LIPUS was evaluated by using visual analogue score of pain (VAS) and changes of function index. Results: after 2 weeks of LIPUS treatment, 琛，

本文編號：1845790