繼發(fā)性甲狀旁腺功能亢進(jìn)癥57例手術(shù)治療臨床分析
發(fā)布時(shí)間:2018-04-26 06:34
本文選題:甲狀旁腺切除術(shù) + 尿毒癥。 參考:《重慶醫(yī)學(xué)》2017年18期
【摘要】:目的探討甲狀旁腺全部切除加自體移植術(shù)(PTX+AT)治療尿毒癥維持性透析患者繼發(fā)性甲狀旁腺功能亢進(jìn)癥(SHPT)的臨床療效及術(shù)后的補(bǔ)鈣治療措施。方法對(duì)2015年3-8月于南京醫(yī)科大學(xué)第一附屬醫(yī)院/江蘇省人民醫(yī)院腎內(nèi)科接受PTX+AT治療的57例SHPT患者臨床資料進(jìn)行回顧性分析,觀察手術(shù)前后血清全段甲狀旁腺激素(iPTH)、血鈣及臨床癥狀等變化。結(jié)果術(shù)后不同時(shí)間[即刻、20min、第2天、第4天血iPTH分別為(288.57±194.71)、(185.00±99.28)、(83.83±58.26)、(17.91±15.60)pg/mL],較術(shù)前iPTH[(2 395.80±829.04)pg/mL]明顯下降(P0.01);術(shù)后4、8、24、72h血鈣分別為(2.34±0.32)、(2.16±0.37)、(2.16±0.27)、(2.25±0.25)mmol/L,較術(shù)前血鈣(2.61±0.25)mmol/L明顯下降(P0.05);骨痛、皮膚瘙癢等臨床癥狀明顯改善。結(jié)論 PTX+AT可以有效地治療尿毒癥SHPT,術(shù)后及時(shí)補(bǔ)鈣可減少低鈣血癥的發(fā)生。
[Abstract]:Objective to investigate the clinical effect of total parathyroidectomy and autograft PTX ATT in the treatment of secondary hyperparathyroidism in uremic maintenance dialysis patients. Methods the clinical data of 57 patients with PTX treated with PTX AT in Department of Nephrology, first affiliated Hospital of Nanjing Medical University / people's Hospital of Jiangsu Province from March to August 2015 were retrospectively analyzed. The changes of serum total parathyroid hormone iPTHG, serum calcium and clinical symptoms were observed before and after operation. 緇撴灉鏈悗涓嶅悓鏃墮棿[鍗沖埢,20min,絎,
本文編號(hào):1804924
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