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鎂合金骨板組織液流場分析及表面織構優(yōu)化

發(fā)布時間:2018-04-23 11:08

  本文選題:鎂合金骨板 + 流場分析。 參考:《濟南大學》2016年碩士論文


【摘要】:目前臨床主要應用的固定植入體是不銹鋼和鈦合金骨板。這些骨板雖然能促進骨愈合,起到加強內固定的作用,但是會給患者帶來負重感和二次手術的傷害。而鎂合金骨板密度和人體骨相近,鎂元素能被人體吸收,促進骨骼生長,無負重感,減少二次手術的傷害。故本文通過對鎂合金骨板與斷骨之間流場進行分析,研究攜帶藥物的組織液的流動狀態(tài)及分布規(guī)律,研究鎂合金骨板表面不同織構型式對組織液流動狀態(tài)的影響。通過有無織構的組織液流場分析,對織構的結構進行設計和優(yōu)化。經過分析與計算,設計截面為正方形、半圓形、正六邊形凹坑的三種鎂合金骨板表面織構。通過在鎂合金骨板表面添加織構,增加鎂合金骨板與脛骨組織的接觸面積,同時增大鎂合金骨板表面的載藥量。對鎂合金骨板表面流場進行數學建模,通過對流場的速度、壓力、剪切應力的計算與分析,為鎂合金骨板表面織構優(yōu)化與分析打下堅實基礎。本文分析鎂合金骨板表面組織液與藥物組成的兩相流的流場分析。通過正方形、半球形、正六邊形三種單織構的骨板流場與無織構骨板流場兩相流的比較分析,得出有表面織構的鎂合金骨板流場的速度、壓力、剪切應力較大,能促進骨骼愈合。而三種單織構的流場中,半球形織構的鎂合金骨板更能促進人體骨骼愈合的速度。單織構流場的分析為鎂合金表面織構的優(yōu)化打下堅實的基礎。通過比較分析鎂合金骨板表面單織構的半球形流場與多織構的半球形流場發(fā)現,多織構流場與單織構流場差別不大,對有限元分析結果與數值計算結果進行相互對比,得出誤差在允許范圍內,說明半球形織構應用到鎂合金骨板上是合理的。把組織液與藥物看成一種流場,對鎂合金骨板表面的半球形織構進行流場分析。通過改變半球形織構的深-徑比來優(yōu)化半球形織構,分析改變深-徑比后的半球形流場,對流場的速度、剪切應力、壓力進行分析比較,把有限元分析的結果與數值計算結果進行對比,誤差在允許的范圍內,得出深-徑比為1:2的半球形織構更能促進骨骼的生長與人體康復速度。通過流-固耦合分析,得出鎂合金骨板添加表面織構滿足強度要求。
[Abstract]:The main clinical implants are stainless steel and titanium alloy bone plates. These plates, while promoting bone healing and strengthening internal fixation, can cause weight-bearing and secondary surgery injuries to patients. The density of magnesium alloy bone plate is similar to that of human bone. Magnesium element can be absorbed by human body, promote bone growth, have no sense of weight, and reduce the injury of secondary operation. Therefore, the flow field between magnesium alloy bone plate and broken bone is analyzed in this paper, and the flow state and distribution of tissue liquid carrying medicine are studied, and the influence of different texture types on the flow state of magnesium alloy bone plate is studied. The texture structure was designed and optimized by analyzing the flow field of tissue liquid with or without texture. Through analysis and calculation, the surface texture of magnesium alloy bone plate with square, semicircular and hexagonal pits is designed. By adding texture to the surface of magnesium alloy bone plate, the contact area between magnesium alloy bone plate and tibial tissue was increased, and the amount of drug loaded on the surface of magnesium alloy bone plate was increased. The flow field on the surface of magnesium alloy bone plate was modeled. The calculation and analysis of the velocity, pressure and shear stress of the flow field laid a solid foundation for the optimization and analysis of the surface texture of magnesium alloy bone plate. In this paper, the flow field of the two-phase flow on the surface of magnesium alloy bone plate is analyzed. By comparing and analyzing the flow field of bone plate with square, hemispherical and hexagonal single texture and that of non-texture bone plate, the velocity, pressure and shear stress of the flow field of magnesium alloy bone plate with surface texture are obtained. Can promote bone healing. In the flow field of three kinds of single texture, the magnesium alloy bone plate with hemispherical texture can promote the speed of bone healing. The analysis of single texture flow field lays a solid foundation for the optimization of magnesium alloy surface texture. By comparing and analyzing the hemispherical flow field of single texture on the surface of magnesium alloy bone plate and the hemispherical flow field of multi-texture, it is found that there is little difference between multi-texture flow field and single-texture flow field. The finite element analysis results are compared with the numerical results. The error is within the allowable range, which indicates that the hemispherical texture applied to the magnesium alloy bone plate is reasonable. The flow field of the hemispherical texture on the surface of magnesium alloy bone plate was analyzed by considering the tissue fluid and the drug as a flow field. The hemispherical texture is optimized by changing the ratio of depth to diameter of hemispherical texture, and the velocity, shear stress and pressure of the hemispherical flow field, the velocity of the flow field, the shear stress and the pressure of the hemispherical flow field after changing the depth-diameter ratio are analyzed and compared. Comparing the results of finite element analysis with numerical results, the error is within the allowable range, and it is concluded that the hemispherical texture with the ratio of depth to diameter of 1:2 can promote the growth of bone and the recovery speed of human body. Through fluid-solid coupling analysis, it is concluded that the surface texture of magnesium alloy bone plate can meet the strength requirement.
【學位授予單位】:濟南大學
【學位級別】:碩士
【學位授予年份】:2016
【分類號】:R687;R318.08

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