本文選題：黏蛋白1(MUC1) + 肝內(nèi)膽管結(jié)石病��； 參考：《青島大學(xué)》2015年碩士論文

【摘要】：目的:探討肝內(nèi)膽管結(jié)石病變膽管MUC1表達情況及與CA199表達有無相關(guān)性。方法:收集肝內(nèi)膽管結(jié)石手術(shù)標(biāo)本46例作為實驗組,選取肝臟血管瘤15例作為對照組,檢測術(shù)前空腹外周血清MUC1及CA199,檢測術(shù)后標(biāo)本的MUC1表達。結(jié)果:實驗組與對照組血清中MUCl及CA199表達差異有統(tǒng)計學(xué)意義,實驗組及對照組標(biāo)本中MUCl表達差異有統(tǒng)計學(xué)意義。結(jié)論:肝內(nèi)膽管結(jié)石病人血液及膽管組織中MUC1表達較高。肝內(nèi)膽管結(jié)石患者血清中MUC1及CA199可同時增高。
[Abstract]:Objective: to investigate the expression of MUC1 in bile duct with intrahepatic cholelithiasis and its correlation with CA199 expression.Methods: 46 cases of intrahepatic cholelithiasis were collected as experimental group and 15 cases of hepatic hemangioma as control group. Fasting peripheral blood plasma MUC1 and CA199were detected before and after operation. The expression of MUC1 was detected after operation.Results: there were significant differences in the expression of MUCl and CA199 between the experimental group and the control group, and the expression of MUCl in the experimental group and the control group.Conclusion: the expression of MUC1 in blood and bile duct tissues of patients with intrahepatic cholelithiasis is higher.Serum MUC1 and CA199 in patients with intrahepatic cholelithiasis were increased simultaneously.
【學(xué)位授予單位】：青島大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2015
【分類號】：R657.42

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本文編號：1769648