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腦膿腫不同時期手術干預的療效分析

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  本文選題:腦膿腫 切入點:膿腫引流術 出處:《中國臨床神經外科雜志》2016年09期  論文類型:期刊論文


【摘要】:目的探討腦膿腫不同時期手術方法及其療效。方法回顧性分析2010年1月~2015年12月收治的52例腦膿腫的臨床資料,依據(jù)病理分期及手術方式分為4組:化膿期引流術組14例,化膿期切除術組13例,膿腫形成期引流術組10例,膿腫形成期切除術組15例。術后隨訪60 d,分析各組療效、病死率、復發(fā)率及術后住院天數(shù)、神經癥狀緩解時間。結果 4組性別比、年齡分布、入院GCS評分無明顯差異(P0.05)。膿腫形成期切除術組中位住院天數(shù)較膿腫形成期引流術組明顯延長(P0.05),而與化膿期引流術組、化膿期切除術組均無明顯差異(P0.05)。化膿期引流術組病死率明顯高于其他3組(P0.05)。4組術后復發(fā)率均無明顯差異(P0.05)。膿腫形成期切除術組中位神經癥狀緩解時間最短(P0.05)。結論膿腫形成期引流術后住院天數(shù)較長,但神經癥狀緩解較快;化膿期出現(xiàn)腦疝征象時,應積極手術干預,必要時行去骨瓣減壓術。
[Abstract]:Objective to investigate the operative methods and curative effect of brain abscess at different stages. Methods the clinical data of 52 cases of brain abscess from January 2010 to December 2015 were retrospectively analyzed. According to the pathological stages and surgical methods, the patients were divided into 4 groups: 14 cases in the drainage group during purulent period. There were 13 cases in the purulent resection group, 10 cases in the drainage group during abscess formation, and 15 cases in the abscess formation stage resection group. All patients were followed up for 60 days, and the curative effect, mortality, recurrence rate and postoperative hospitalization days were analyzed. Results there was no significant difference in sex ratio, age distribution and admission GCS score among the four groups. The median length of stay in the abscess formation stage group was significantly longer than that in the abscess stage drainage group, but it was significantly longer than that in the suppurative drainage group. There was no significant difference in the postoperative recurrence rate in the purulent resection group (P 0.05). The mortality of the drainage group was significantly higher than that in the other three groups (P 0.054.There was no significant difference in postoperative recurrence rate between the two groups. Conclusion the median neurologic symptom relief time in the abscess formation stage resection group is the shortest (P 0.05). The length of hospital stay after drainage during abscess formation was longer. But the neurological symptoms were relieved more quickly, and when the symptoms of cerebral hernia appeared in the stage of pyosis, the operative intervention should be actively carried out, and the decompression of bone flap should be performed when necessary.
【作者單位】: 新疆醫(yī)科大學第一附屬醫(yī)院神經外科;
【基金】:新疆維吾爾自治區(qū)青年科技人才專項科研項目(2015Y35)
【分類號】:R651.1

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