本文選題：乳腺腫瘤　切入點：乳房切除術(shù)　出處：《中國普通外科雜志》2017年05期 　論文類型：期刊論文

【摘要】：目的:探討腫瘤整形技術(shù)應(yīng)用于早期乳腺癌保乳術(shù)的療效及安全性。方法:回顧性分析2011年8月—2016年8月139例應(yīng)用腫瘤整形技術(shù)進行保乳手術(shù)治療的I~II期乳腺癌患者臨床資料,并與同期1 271例行乳腺癌改良根治術(shù)的I~II乳腺癌患者的遠期效果比較。結(jié)果:139例患者中,133例采用體積易位技術(shù)(局部腺體組織瓣轉(zhuǎn)移修補法)進行保乳手術(shù),其中45例同時接受對側(cè)縮乳術(shù),6例采用體積置換技術(shù)(自體組織移植修補法);78例行前哨淋巴結(jié)活檢術(shù),61例接受腋窩淋巴結(jié)清掃術(shù)。139例乳腺癌患者切除組織標本重30~187 g,平均69.5 g;美容效果評定結(jié)果為優(yōu)秀79例(56.8%)、良好47例(33.8%)、一般10例(7.2%)、差3例(2.2%)。術(shù)后隨訪時間為3~63個月,平均28.8個月;與行改良根治術(shù)的患者比較,行腫瘤整形保乳術(shù)患者的術(shù)后2年局部復(fù)發(fā)率(4.3%vs.4.1%),總生存率(95.7%vs.95.5%),無病生存率(85.6%vs.85.3%)均無統(tǒng)計學差異(均P0.05)。結(jié)論:應(yīng)用腫瘤整形技術(shù)對早期乳腺癌進行保乳手術(shù)具有較好的腫瘤學安全性和滿意的美容效果,遠期效果與改良根治術(shù)相當。選擇適合的病例和合理的整形技術(shù),是腫瘤整形保乳術(shù)取得最佳的術(shù)后效果的關(guān)鍵。
[Abstract]:Objective: to evaluate the efficacy and safety of tumor plastic surgery in the treatment of early breast cancer. Methods: the clinical data of 139 patients with stage II breast cancer undergoing breast conserving surgery from August 2011 to August 2016 were retrospectively analyzed. The results were compared with that of 1 271 patients undergoing modified radical mastectomy in the same period. Results among 139 cases of breast cancer, 133 cases were treated with volume translocation technique (local glandular tissue flap transfer and repair) for breast conserving operation. Among them, 45 cases received contralateral mammary constriction and 6 cases underwent volume replacement (autologous tissue transplantation and repair method 78 cases sentinel lymph node biopsy 61 cases received axillary lymph node dissection .139 cases of breast cancer patients resected tissue weight. The results of beauty evaluation were excellent 79 cases (56.8%), good 47 cases (33.8%), average 10 cases (7.2g) and 3 cases (2.2g). The follow-up time was 3 ~ 63 months. Mean 28.8 months; compared with patients undergoing modified radical mastectomy, The local recurrence rate of patients undergoing plastic surgery and breast conserving surgery was 4.3vs.4.1. The overall survival rate was 95.7vs.95.50.There was no statistical difference in the disease-free survival rate of 85.6v s.85.3.Conclusion: it is better to use tumor plastic surgery in early breast cancer surgery. Safety and satisfactory cosmetic effects of oncology, The long-term effect is the same as that of modified radical mastectomy. The key to obtain the best postoperative effect is to select suitable cases and reasonable plastic techniques.
【作者單位】： 重慶市腫瘤研究所乳腺中心;
【基金】：重慶市醫(yī)學科研計劃基金資助項目(20141018)
【分類號】：R737.9

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