本文選題：高壓氧　切入點：仙桃草　出處：《山東醫(yī)藥》2017年11期 　論文類型：期刊論文

【摘要】：目的觀察用高壓氧聯(lián)合仙桃草飼喂治療兔骨缺損的效果。方法選用新西蘭大白兔80只制作兔骨缺損模型,隨機分為A、B、C、D組,A組給予高壓氧聯(lián)合仙桃草飼喂治療、B組給予高壓氧治療、C組給予仙桃草飼喂治療,D組為正常對照不用藥。分別于治療后第2、4、8、12周分批處死各組兔,在電鏡、光鏡下計數(shù)新生骨痂成骨細胞數(shù)及新生骨小梁面積比,電鏡下觀察成骨細胞和骨股原纖維形態(tài)。結(jié)果光鏡下治療后2、4、8、12周A組兔骨痂新生骨小梁鏡下面積比和成骨細胞計數(shù)高于B、C、D組(P均0.05),B、C組兔骨痂新生骨小梁鏡下面積比和成骨細胞計數(shù)高于D組(P均0.05)。電鏡下觀察,與B、C、D組比較,A組成骨細胞細胞器最發(fā)達,骨膠原纖維排列整齊,分布均勻。結(jié)論高壓氧聯(lián)合仙桃草飼喂治療兔骨缺損,可明顯增強成骨細胞增殖分化及成骨能力,加快骨小梁生成,促進骨缺損的愈合,效果強于單用高壓氧或者仙桃草者。
[Abstract]:Objective to observe the effect of hyperbaric oxygen (HBO) combined with Xiantao grass on the treatment of rabbit bone defect. The rabbits in group A were randomly divided into two groups: group A: hyperbaric oxygenation combined with Peach grass feeding. Group B was given hyperbaric oxygen therapy and group C was given hyperbaric oxygen therapy. Group D was treated with hyperbaric oxygen as control group, and rabbits in group D were killed in batches at the 12th week after treatment, and the rabbits were killed under electron microscope. The number of osteoblasts and the ratio of trabecular area to trabeculae were counted under light microscope. Results the area ratio and osteoblast count of callus of group A were higher than those of group B (0. 05) and group B (0. 05). Results the area ratio and osteoblast count of callus of group A were higher than those of group B (0. 05%) at 12 weeks after light microscope. Ratio of osteoblasts and osteoblast count in group D were higher than those in group D (P 0.05). The osteoblasts in group A had the most developed organelles, the collagenous fibers were arranged neatly and evenly distributed. Conclusion Hyperbaric oxygen combined with Prunus chinensis can obviously enhance the proliferation, differentiation and osteogenesis of osteoblasts in rabbits with bone defect. To accelerate trabeculae formation and promote bone defect healing, the effect is better than that of hyperbaric oxygen alone or peaches.
【作者單位】： 廣西壯族自治區(qū)人民醫(yī)院;
【基金】：廣西中醫(yī)藥管理局中醫(yī)藥科技專項面上課題(GZPT1242) 廣西適宜衛(wèi)生技術(shù)研發(fā)推廣人才小高地項目(006011)
【分類號】：R683

【相似文獻】

相關(guān)期刊論文 前10條

1 孫靜如;;仙桃草的臨床應用[J];江西醫(yī)藥;1965年10期

2 唐玉虬;;仙桃草蟲治效考證[J];江蘇醫(yī)藥;1976年01期

3 楊啟權(quán);;仙桃草散治外傷[J];四川中醫(yī);1985年07期

4 楊成梓,凌偉堅,陳健斌;兩種仙桃草的本草考證[J];中藥材;2003年11期

5 張少鶴;周宜軒;;仙桃草沖劑治療上消化道出血52例[J];中西醫(yī)結(jié)合雜志;1985年01期

6 朱恒興;仙桃草治療肺結(jié)核咯血90例[J];江蘇中醫(yī);2000年10期

7 宋光偉;邢茂;王偉;田華;葛勤;;HPLC法測定仙桃草中木犀草素的含量[J];中國藥房;2009年15期

8 張鐘愛;;六味骨仙飲[J];江蘇中醫(yī)藥;2014年01期

9 周玲;;地錦草的藥用與食療[J];東方藥膳;2007年04期

10 ;[J];;年期

相關(guān)會議論文 前1條

1 邢茂;宋光偉;王偉;;HPLC法測定仙桃草中木犀草素的含量[A];2008年中國藥學會學術(shù)年會暨第八屆中國藥師周論文集[C];2008年

相關(guān)碩士學位論文 前1條

1 楊勇;高壓氧聯(lián)合中草藥仙桃草治療骨缺損的實驗研究[D];廣西醫(yī)科大學;2014年

，

本文編號：1565106