本文關(guān)鍵詞： 退行性腰椎滑脫 腦脊液漏 硬脊膜損傷 危險(xiǎn)因素　出處：《中國脊柱脊髓雜志》2016年07期 　論文類型：期刊論文

【摘要】：目的:探討退行性腰椎滑脫術(shù)后腦脊液漏的發(fā)生率及危險(xiǎn)因素,為臨床預(yù)防腦脊液漏的發(fā)生提供依據(jù)。方法:收集我院2008年1月~2014年12月收治的201例單節(jié)段退行性腰椎滑脫初次手術(shù)患者的病史資料,根據(jù)是否并發(fā)腦脊液漏分為觀察組和對照組,分析患者的性別、年齡、吸煙史、飲酒史、是否合并糖尿病、體重指數(shù)(body mass index,BMI)、手術(shù)方式[腰椎后路椎間融合(PLIF)或經(jīng)椎間孔椎間融合(TLIF)]、滑脫部位、滑脫程度(Meyerding分度)、手術(shù)時(shí)間及術(shù)者年資與術(shù)后腦脊液漏發(fā)生率的關(guān)系。結(jié)果:201例患者中共有20例并發(fā)腦脊液漏,發(fā)生率為9.95%(20/201)。單因素分析結(jié)果顯示兩組病例在手術(shù)方式、滑脫程度、手術(shù)時(shí)間、術(shù)者年資方面差異有統(tǒng)計(jì)學(xué)意義(P0.05);多因素Logistic回歸分析顯示,手術(shù)方式(PLIF與TLIF相比:OR=4.572,95%CI=1.192~17.534)、滑脫程度(Ⅰ度滑脫與Ⅱ度及Ⅱ度以上滑脫相比:OR=0.172,95%CI=0.059~0.500)是退行性腰椎滑脫術(shù)后并發(fā)腦脊液漏的危險(xiǎn)因素(P0.05)。結(jié)論:手術(shù)方式和滑脫程度影響退行性腰椎滑脫術(shù)后腦脊液漏的發(fā)生率。
[Abstract]:Objective: to investigate the incidence and risk factors of cerebrospinal fluid leakage after degenerative lumbar spondylolisthesis. Methods: from January 2008 to December 2014, 201 patients with single segmental degenerative lumbar spondylolisthesis were treated in our hospital. According to whether cerebrospinal fluid leakage is complicated or not, they are divided into observation group and control group. The sex, age, smoking history, drinking history and diabetes mellitus of the patients were analyzed. Body mass index (mass), body mass index (BMI), surgical procedure [posterior lumbar intervertebral fusion (PLIFF) or transforaminal fusion (TLIF)], site of spondylolisthesis, Results 20 of 201 patients (9.95% 20 / 201) had cerebrospinal fluid leakage. Univariate analysis showed that there were two groups of patients in the two groups, and the results of univariate analysis showed that there were two groups of patients with cerebrospinal fluid leakage (CSF leakage), and the results of univariate analysis showed that the two groups had cerebrospinal fluid leakage (CSF) in the two groups, and the results of univariate analysis showed that there were 20 cases of cerebrospinal fluid leakage in the two groups. There were significant differences in degree of slippage, time of operation, seniority of the operator (P 0.05). Multivariate Logistic regression analysis showed that, Compared with TLIF, PLIF is a risk factor for cerebrospinal fluid leakage after degenerative spondylolisthesis. Conclusion: surgical procedure and degree of spondylolisthesis influence the degree of spondylolisthesis. Conclusion: the degree of spondylolisthesis and the degree of spondylolisthesis are the risk factors of cerebrospinal fluid leakage after degenerative spondylolisthesis. Conclusion: the degree of spondylolisthesis and the degree of spondylolisthesis affect the degree of spondylolisthesis and the risk factor of cerebrospinal fluid leakage after degenerative spondylolisthesis. Incidence of cerebrospinal fluid leakage after lumbar spondylolisthesis.
【作者單位】： 陸軍總醫(yī)院骨科;
【分類號】：R687.3

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