本文關(guān)鍵詞： 乳腺癌 淋巴結(jié)清掃術(shù) 淋巴水腫 生活質(zhì)量　出處：《中國(guó)現(xiàn)代醫(yī)學(xué)雜志》2017年29期 　論文類型：期刊論文

【摘要】：目的在探討乳腺癌淋巴結(jié)清掃術(shù)中保留上肢淋巴結(jié)對(duì)淋巴水腫及生活質(zhì)量的影響。方法選取2013年1月-2014年12月于貴州省人民醫(yī)院乳腺科收治的100例T1-3No Mo期乳腺癌患者,根據(jù)患者及其家屬協(xié)商選擇的手術(shù)方法將研究對(duì)象分為觀察組和對(duì)照組,每組各50例。觀察組術(shù)前以納米炭混懸液行經(jīng)上臂逆行腋窩淋巴結(jié)示蹤術(shù);對(duì)照組行腋窩淋巴結(jié)清掃術(shù)。于術(shù)后1、6及12個(gè)月時(shí)對(duì)兩組患者進(jìn)行隨訪,記錄并比較兩組患者隨訪期間各時(shí)間點(diǎn)患側(cè)比健側(cè)上肢臂圍增加的百分比,術(shù)后12個(gè)月時(shí)上肢淋巴水腫發(fā)生情況,各時(shí)間點(diǎn)乳腺癌患者生命質(zhì)量測(cè)定量表(FACT-B)評(píng)分。結(jié)果兩組術(shù)后1、6及12個(gè)月患側(cè)比健側(cè)上肢臂圍增加的百分比比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。此外,兩組12個(gè)月時(shí)上肢淋巴水腫總發(fā)生率比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05);在預(yù)防上肢淋巴水腫的效果方面,觀察組的優(yōu)良率高于對(duì)照組(P0.05)。與治療前相比,觀察組的生活質(zhì)量評(píng)分降低,且兩組隨訪期間各時(shí)間點(diǎn)的評(píng)分比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論保留上肢淋巴結(jié)的乳腺癌淋巴結(jié)清掃術(shù)可以有效地預(yù)防患者上肢淋巴水腫,改善患者的生活質(zhì)量,值得在臨床上推廣使用。
[Abstract]:The quality of life and effects of retaining the edema of upper limb lymph nodes in the lymph to investigate lymph node dissection in breast cancer. Methods from January 2013 -2014 year in December in the breast Department of Guizhou People's Hospital from 100 cases of T1-3No patients with stage Mo breast cancer patients and their families, according to the consultation operation methods selected subjects were divided into observation group and control group. 50 patients in each group. The patients of the observation group with carbon nanoparticles suspension arm underwent retrograde axillary lymph node tracer technique; the control group underwent axillary lymph node dissection. After 1,6 and 12 months of two groups were recorded and recorded during percentage were compared between the two groups at each time point with follow-up side than the healthy side upper limb arm circumference increased, after 12 months of surgery of upper extremity lymphedema incidence scale measuring quality of life in patients with breast cancer at each time point (FACT-B) score. The results of two groups of 1,6 and 12 months after the affected side than The contralateral upper arm circumference increased the percentage of comparison, the difference was statistically significant (P0.05). In addition, the two groups at 12 months of upper limb lymphedema incidence of comparison, the difference was statistically significant (P0.05); in the prevention of upper extremity lymphedema, observation group good rate higher than the control group (P0.05). Compared with before treatment, life quality scores in the observation group decreased, and the two groups during follow-up at each time point were compared, the difference was statistically significant (P0.05). Conclusion preservation of upper limb lymph node of breast cancer lymph node dissection can effectively prevent upper extremity lymph edema patients, improve the quality of life of patients, is worthy to be popularized in clinical.

【作者單位】： 貴州省人民醫(yī)院乳腺外科;
【基金】：貴州省科學(xué)技術(shù)基金項(xiàng)目[No:黔科合J字(2009)2200號(hào)]
【分類號(hào)】：R737.9
【正文快照】： 乳腺癌是女性最常見的惡性腫瘤之一。據(jù)統(tǒng)計(jì),每年10萬(wàn)名女性中就新增81.1例乳腺癌患者,5年生存率為82%[1]。對(duì)于乳腺癌的治療,乳腺癌根治術(shù)一直是主流的治療手段之一[2]。但是患者術(shù)后同側(cè)上肢淋巴水腫的發(fā)生率較高,達(dá)7%[3]。以往的研究發(fā)現(xiàn),與腋窩淋巴結(jié)清掃(axillary lymph

【相似文獻(xiàn)】

相關(guān)期刊論文 前5條

1 賈實(shí);李建一;張文海;張揚(yáng);費(fèi)翔;;乳腺癌腋窩清掃術(shù)中上肢淋巴結(jié)定位及轉(zhuǎn)移規(guī)律的研究[J];中國(guó)醫(yī)科大學(xué)學(xué)報(bào);2012年05期

2 王志華;趙建娥;張騰華;耿偉民;孫玉梅;;乳腺癌腋窩淋巴結(jié)清掃術(shù)中選擇性保留上肢淋巴結(jié)對(duì)預(yù)防上肢淋巴水腫的作用[J];中國(guó)普外基礎(chǔ)與臨床雜志;2011年06期

3 李卓毅;范揚(yáng)航;鄭海波;陳捷鑫;張澤淳;吳智勇;;乳腺癌腋窩淋巴結(jié)清掃術(shù)上肢淋巴結(jié)解剖學(xué)定位的可行性[J];廣東醫(yī)學(xué);2013年07期

4 李榮榮;曹鵬;霍介格;王小寧;;乳腺癌術(shù)后上肢淋巴結(jié)水腫中西醫(yī)治療的研究進(jìn)展[J];世界中西醫(yī)結(jié)合雜志;2013年01期

5 何春;許辰陽(yáng);黃興偉;黃謀清;袁火忠;張功亮;肖震宇;習(xí)勛;;乳腺癌胸腔鏡內(nèi)乳淋巴結(jié)清掃術(shù)的臨床研究[J];中國(guó)當(dāng)代醫(yī)藥;2013年31期

相關(guān)碩士學(xué)位論文 前1條

1 程玉;乳腺癌乳房切除術(shù)后立即乳房重建的腫瘤學(xué)安全性的系統(tǒng)評(píng)價(jià)[D];山西醫(yī)科大學(xué);2017年

，

本文編號(hào)：1443388