【摘要】：無(wú)針注射是利用藥液的高速射流進(jìn)入被注射體內(nèi),從而完成注射的技術(shù)過(guò)程。隨著臨床需要的推動(dòng)和科學(xué)技術(shù)的發(fā)展,無(wú)針注射器技術(shù)呈現(xiàn)出蓬勃發(fā)展的態(tài)勢(shì),美國(guó)和歐洲已經(jīng)有不同類(lèi)型的商品面世,我國(guó)對(duì)無(wú)針注射的研究剛剛起步,目前還沒(méi)有針對(duì)國(guó)內(nèi)需求的產(chǎn)品上市。 本文主要研究的內(nèi)容如下： 1.介紹了國(guó)內(nèi)外已有的無(wú)針注射器技術(shù),總結(jié)了現(xiàn)有無(wú)針注射器的技術(shù)指標(biāo)及研究開(kāi)發(fā)路線； 2.進(jìn)行無(wú)針注射器總體方案的設(shè)計(jì),根據(jù)功能,將無(wú)針注射器分為機(jī)械結(jié)構(gòu)部分、液壓回路部分和電氣控制部分,對(duì)各部分分析并確定最終采用的方案； 3.根據(jù)分析及要求細(xì)化結(jié)構(gòu),對(duì)關(guān)鍵參數(shù)進(jìn)行理論計(jì)算,設(shè)計(jì)得到產(chǎn)品三維模型,并且簡(jiǎn)化設(shè)計(jì)原理樣機(jī),驗(yàn)證無(wú)針注射器原理的可行性； 4.基于前人設(shè)計(jì)的小孔噴射模型和液體撞擊模型,對(duì)設(shè)計(jì)的機(jī)器進(jìn)行仿真,得到對(duì)于各個(gè)高壓空氣彈簧的噴射特性分布； 5.進(jìn)行穩(wěn)定性實(shí)驗(yàn)、高速攝像實(shí)驗(yàn)、注射仿生材料實(shí)驗(yàn)以及離體豬肉注射實(shí)驗(yàn),四個(gè)實(shí)驗(yàn)層層遞進(jìn),逐步證實(shí)了無(wú)針注射器原理樣機(jī)的穩(wěn)定性、模型仿真數(shù)據(jù)與實(shí)驗(yàn)數(shù)據(jù)的吻合度以及注射形態(tài)穩(wěn)定性,并且驗(yàn)證了隨著注射動(dòng)力的增加,注射深度隨之增加的結(jié)論。 本文設(shè)計(jì)了機(jī)械機(jī)構(gòu)、電氣控制,對(duì)噴射過(guò)程進(jìn)行理論分析,加工調(diào)試樣機(jī),并開(kāi)展了多種實(shí)驗(yàn),驗(yàn)證了樣機(jī)的可行性和可靠性,完成了新產(chǎn)品開(kāi)發(fā)的前期工作,為后續(xù)的新產(chǎn)品開(kāi)發(fā)的完善奠定了堅(jiān)實(shí)的基礎(chǔ)。
[Abstract]:Needle-free injection is the technical process of injection by using the high-speed jet of the liquid into the injected body. With the promotion of clinical needs and the development of science and technology, needle free syringe technology has shown a vigorous development trend, the United States and Europe have been different types of commodities, the study of needle free injection in China has just started. At present, there is no domestic demand for products on the market. The main contents of this paper are as follows: 1. This paper introduces the existing syringe technology at home and abroad, summarizes the technical index and research and development route of the existing syringe. 2. According to the function, the syringe is divided into mechanical structure part, hydraulic circuit part and electrical control part. According to the analysis and the requirement to refine the structure, the key parameters are calculated theoretically, the product 3D model is designed, and the prototype of the design principle is simplified to verify the feasibility of the principle of the needle less syringe. 4. Based on the small hole injection model and liquid impact model designed by predecessors, the designed machine is simulated and the spray characteristic distribution for each high-pressure air spring is obtained. 5. The stability experiment, high speed camera experiment, injection bionic material experiment and in vitro pork injection experiment were carried out. Four experiments were carried out step by step, which gradually proved the stability of the principle prototype of the needle free syringe. The consistency of the model simulation data with the experimental data and the stability of the injection morphology are verified, and the conclusion that the injection depth increases with the increase of the injection power is verified. In this paper, the mechanical mechanism, electrical control, theoretical analysis of the injection process, processing and debugging of the prototype are designed, and a variety of experiments are carried out to verify the feasibility and reliability of the prototype, and the preliminary work of the new product development is completed. For the subsequent development of new products to establish a solid foundation.
【學(xué)位授予單位】：浙江大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2012
【分類(lèi)號(hào)】：TH789

【參考文獻(xiàn)】

相關(guān)期刊論文 前8條

1 趙萬(wàn)生,韋紅雨,劉維東,狄士春;應(yīng)用線電極磨削法的電火花微孔加工[J];電加工;1997年03期

2 周旭;王伽伯;肖小河;;無(wú)針注射給藥系統(tǒng)及應(yīng)用[J];解放軍藥學(xué)學(xué)報(bào);2005年06期

3 王伽伯;周旭;金城;肖小河;;無(wú)針?lè)勰┳⑸浣o藥技術(shù)研究進(jìn)展[J];解放軍藥學(xué)學(xué)報(bào);2006年04期

4 沈星;劉永剛;裘進(jìn)浩;;RAINBOW壓電陶瓷與形狀記憶合金的集成[J];金屬熱處理;2006年08期

5 張玉榮,余永剛,栗保明;高速液體射流流動(dòng)特性的實(shí)驗(yàn)測(cè)試方法[J];力學(xué)與實(shí)踐;1999年05期

6 金京;;無(wú)針安全注射器的設(shè)計(jì)[J];生物醫(yī)學(xué)工程研究;2007年03期

7 陳凱;周華;;彈簧式液體噴射注射過(guò)程的建模及實(shí)驗(yàn)研究[J];中國(guó)生物醫(yī)學(xué)工程學(xué)報(bào);2010年01期

8 陳凱;呂永桂;;一種新型液體噴射注射器的研制[J];中國(guó)醫(yī)療器械雜志;2009年06期

相關(guān)碩士學(xué)位論文 前3條

1 應(yīng)人龍;基于噴射理論的無(wú)針注射系統(tǒng)建模及實(shí)驗(yàn)研究[D];浙江大學(xué);2008年

2 曾莉群;無(wú)針注射器研發(fā)[D];浙江大學(xué);2008年

3 焦坤;無(wú)針注射器測(cè)試評(píng)價(jià)系統(tǒng)的研究[D];華中科技大學(xué);2007年

，

本文編號(hào)：2320173