本文選題：呼吸 + 肝臟運(yùn)動(dòng)��； 參考：《浙江大學(xué)學(xué)報(bào)(工學(xué)版)》2014年09期

【摘要】：為補(bǔ)償肝臟運(yùn)動(dòng),分析呼吸引起的肝臟空間運(yùn)動(dòng)和形變,并嘗試將其簡(jiǎn)化為剛性運(yùn)動(dòng)模型進(jìn)行補(bǔ)償.利用基于表面和基于互信息的3D-3D圖像剛性配準(zhǔn)方法分析4例肝臟空間運(yùn)動(dòng)的規(guī)律并進(jìn)行補(bǔ)償,比較使用手工分割肝臟輪廓和肝臟灰度信息進(jìn)行配準(zhǔn)的結(jié)果及其補(bǔ)償效果,評(píng)估2種思路的可靠性,并進(jìn)一步評(píng)價(jià)剛體運(yùn)動(dòng)模型簡(jiǎn)化的可行性.結(jié)果表明:剛性運(yùn)動(dòng)模型、簡(jiǎn)化的平移運(yùn)動(dòng)模型和矢狀面2D運(yùn)動(dòng)模型在實(shí)際應(yīng)用中具有可行性,此3種模型都可以補(bǔ)償80%以上的呼吸影響;使用肝臟灰度信息比手工分割輪廓建模和補(bǔ)償?shù)慕Y(jié)果更可靠.上述結(jié)論對(duì)在超聲融合多模成像中快速建模和實(shí)時(shí)補(bǔ)償呼吸對(duì)肝臟運(yùn)動(dòng)的影響有一定的參考價(jià)值.
[Abstract]:In order to compensate for liver motion, the spatial movement and deformation of the liver caused by respiration were analyzed and simplified as rigid motion model. The method of 3D-3D image rigid registration based on surface and mutual information was used to analyze the law of liver spatial motion in 4 cases and to compensate for it. The results and the compensation effect of using manual segmentation of liver contour and liver gray level information were compared. The reliability of the two ideas is evaluated and the feasibility of simplification of rigid body motion model is further evaluated. The results show that the rigid motion model, the simplified translational motion model and the sagittal 2D motion model are feasible in practical application, and the three models can compensate more than 80% of the respiratory effects. Using liver gray level information is more reliable than manual segmentation contour modeling and compensation. These conclusions have some reference value for fast modeling and real time compensation of respiration on liver motion in multimode ultrasound fusion imaging.
【作者單位】： 清華大學(xué)生物醫(yī)學(xué)工程學(xué)系;北京大學(xué)腫瘤醫(yī)院;北京市腫瘤防治研究所介入科 惡性腫瘤發(fā)病機(jī)制及轉(zhuǎn)化研究教育部重點(diǎn)實(shí)驗(yàn)室;
【基金】：國(guó)家自然科學(xué)基金資助項(xiàng)目(81271671,81271735)
【分類號(hào)】：R318

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本文編號(hào)：2002199