本文選題：強(qiáng)迫振蕩技術(shù) + 最優(yōu)線性近似法　； 參考：《華南理工大學(xué)》2012年碩士論文

【摘要】：現(xiàn)代社會(huì)的快速發(fā)展使人們對(duì)健康問題愈發(fā)重視，而呼吸類疾病更是越來越成為人類健康的重要威脅。嚴(yán)重急性呼吸綜合癥(SARS，SevereAcuteRespiratorySyndromes)、禽流感和甲流傳染病都在社會(huì)上引起極大地恐慌，它們都無一不與呼吸的重要器官--肺有極大地關(guān)系，可見對(duì)肺組織進(jìn)行及早的預(yù)防與治療有著多么重要的意義。 本課題的出發(fā)點(diǎn)是基于呼吸疾病越來越成為威脅人類健康的主要病因，而在國(guó)內(nèi)雖然醫(yī)療衛(wèi)生事業(yè)取得長(zhǎng)足的進(jìn)步，但是醫(yī)療器械的發(fā)展卻相對(duì)滯后。有鑒于此，本課題提出了基于強(qiáng)迫振蕩技術(shù)的醫(yī)用呼吸監(jiān)測(cè)儀的設(shè)計(jì)，，該設(shè)計(jì)是區(qū)別于傳統(tǒng)的有創(chuàng)的方式，采用無創(chuàng)的方式通過病人的口或是鼻進(jìn)行肺組織的檢測(cè)。 本課題采用理論建模、模塊劃分和臨床試驗(yàn)相結(jié)合的方法進(jìn)行原理性樣機(jī)的研制工作，樣機(jī)分為振蕩發(fā)生器模塊、數(shù)據(jù)采集模塊、數(shù)據(jù)分析模塊和數(shù)據(jù)顯示模塊。振蕩發(fā)生器模塊的作用是提供強(qiáng)迫振蕩技術(shù)新方法所要產(chǎn)生的低幅低頻正弦信號(hào)，提出音圈電機(jī)為核心的伺服控制系統(tǒng)，系統(tǒng)方案提出了前饋控制的雙閉環(huán)策略；數(shù)據(jù)采集模塊是將管道里的壓力和流量信號(hào)用STM32103ZE(STM32)進(jìn)行采集，提出硬件低通濾波和數(shù)字軟件濾波相結(jié)合的方法；數(shù)據(jù)分析模塊提出以最優(yōu)線性近似法和互相干法為基礎(chǔ)的時(shí)域的分析算法對(duì)呼吸阻抗、電抗和呼吸順應(yīng)性在呼氣相和吸氣相均值以數(shù)值和波形進(jìn)行顯示以此判斷肺部的組織狀況，并改進(jìn)了互相干系數(shù)準(zhǔn)則進(jìn)行數(shù)據(jù)有效性的判斷方法；數(shù)據(jù)顯示模塊是將參數(shù)和波形以按鍵切換操作和VGA屏進(jìn)行顯示；在完成上述模塊之后將各模塊進(jìn)行組裝完成了原理性樣機(jī)的研制，最后將研制的樣機(jī)在南方醫(yī)科大學(xué)珠江附屬醫(yī)院ICU進(jìn)行了R-I-E模型和志愿者測(cè)試的臨床實(shí)驗(yàn)，達(dá)到了樣機(jī)的監(jiān)測(cè)肺部狀況的意義。
[Abstract]:With the rapid development of modern society, people pay more attention to health problems, and respiratory diseases are becoming an important threat to human health. Severe Acute Respiratory Syndrome (SARSs) SevereAcute Respiratory Syndromes.Avian Influenza and H1N1 Infectious Diseases have caused great social panic, and none of them is unrelated to the vital organ of breathing-the lung. It can be seen that early prevention and treatment of lung tissue is of great significance. The starting point of this subject is that respiratory diseases are becoming the main cause of threatening human health, but in China, although the medical and health cause has made great progress, the development of medical devices is relatively lagging behind. In view of this, the design of a medical respiratory monitor based on forced oscillation technique is proposed. The design is different from the traditional invasive method, and the non-invasive method is used to detect the lung tissue through the patient's mouth or nose. In this paper, theoretical modeling, module partition and clinical trial are used to develop the prototype. The prototype is divided into oscillation generator module, data acquisition module, data analysis module and data display module. The function of the oscillation generator module is to provide the low amplitude low frequency sinusoidal signal generated by the new method of forced oscillation technology. A servo control system with voice coil motor as the core is proposed. The system scheme proposes a double closed loop strategy for feedforward control. The data acquisition module uses STM32103ZEN STM32 to collect the pressure and flow signals in the pipeline, and puts forward the method of combining hardware low-pass filtering with digital software filtering. In the data analysis module, a time-domain analysis algorithm based on the optimal linear approximation method and the mutual drying method is proposed to analyze the respiratory impedance. Reactance and respiratory compliance in the expiratory phase and inspiratory phase mean value and waveform to judge the lung tissue status, and improved the mutual coefficient criterion for data validity judgment method; The data display module displays the parameters and waveforms by keystroke switching operation and VGA screen. After completing the above modules, the modules are assembled to complete the development of the principle prototype. In the end, the prototype was used in the ICU of Pearl River affiliated Hospital of Southern Medical University to carry out the clinical experiment of R-I-E model and volunteer test, which achieved the significance of monitoring the lung condition of the prototype.
【學(xué)位授予單位】：華南理工大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2012
【分類號(hào)】：R318.6;TP274.2

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