本文選題：疏水性人工晶狀體 + 超精密加工　； 參考：《沈陽(yáng)工業(yè)大學(xué)》2013年碩士論文

【摘要】：疏水性可折疊人工晶狀體具有折射率高、手術(shù)切口小、制造工藝簡(jiǎn)單等優(yōu)點(diǎn)。然而，疏水性材料剛度低，產(chǎn)品的合格率僅為30%或更低，已成為國(guó)際公認(rèn)的人工晶體加工技術(shù)的難題。沈陽(yáng)綠谷生物技術(shù)產(chǎn)業(yè)有限公司在提高疏水性材料表面硬度的基礎(chǔ)上應(yīng)用超精密加工機(jī)床對(duì)其進(jìn)行超精密切削及后處理，對(duì)提高工件的加工精度和產(chǎn)品的合格率具有重要意義。 本文以沈陽(yáng)綠谷生物技術(shù)產(chǎn)業(yè)有限公司引進(jìn)的疏水性人工晶狀體常溫加工技術(shù)為研究對(duì)象，主要研究了3個(gè)方面的問題。首先，研究了人工晶狀體加工機(jī)床Optoform40車床和Microlution-363s銑床的加工能力，金剛石刀具的加工性能以及疏水性材料的特性，為超精密加工人工晶狀體奠定基礎(chǔ)。其次，在人工晶狀體的機(jī)械加工工藝的基礎(chǔ)上，對(duì)該產(chǎn)品在加工過程中存在的問題進(jìn)行研究。闡述了注塑模壓法、低溫加工法和常溫加工法的優(yōu)缺點(diǎn)。注塑模壓法較為復(fù)雜，且模具費(fèi)用高昂進(jìn)而使用低溫法加工人工晶狀體，常溫加工方法是由低溫加工方法發(fā)展而來，通過材料改性將玻璃化轉(zhuǎn)變溫度調(diào)整到10℃~20℃。避免了加工過程的復(fù)雜性和材料的熱脹冷縮。分析了刀具的插補(bǔ)路徑、刀具的垂直偏置和水平偏置、刀尖曲率半徑測(cè)量誤差、誤差復(fù)映、波紋度、靜電充電和切屑等方面對(duì)工件面形加工精度的影響，并提出了相應(yīng)的解決方法。通過加工實(shí)驗(yàn)，確定了主軸轉(zhuǎn)速3000rpm，切削深度分別為0.20mm、0.10mm和0.015mm。最后，人工晶狀體植入后的穩(wěn)定性和居中性，受力時(shí)壓力是否會(huì)傳遞到光學(xué)區(qū)，影響成像質(zhì)量，，為此本文應(yīng)用ANSYS軟件模擬人工晶狀體植入，植入后人工晶狀體應(yīng)緊貼囊袋，避免術(shù)后白內(nèi)障發(fā)生。 人工晶狀體加工實(shí)驗(yàn)驗(yàn)證了文中提出的解決方法，提高工件合格率�？偨Y(jié)全文研究?jī)?nèi)容并對(duì)人工晶狀體模擬分析等需要進(jìn)一步研究的工作進(jìn)行了展望。
[Abstract]:Hydrophobic foldable intraocular lens has the advantages of high refractive index, small incision and simple manufacturing process. However, the stiffness of hydrophobic materials is low, the qualified rate of products is only 30% or less, which has become an internationally recognized problem of IOL processing technology. On the basis of improving the surface hardness of hydrophobic materials, Shenyang Green Valley Biotechnology Industry Co., Ltd. uses ultra-precision machining machine tools to carry out ultra-precision cutting and post-processing, which is of great significance to improve the machining accuracy of workpieces and the qualified rate of products. In this paper, the hydrophobic intraocular lens processing technology introduced by Shenyang Green Valley Biotechnology Industry Co., Ltd. Firstly, the machining ability of Optoform40 lathe and Microlution-363s milling machine, the machining performance of diamond tools and the characteristics of hydrophobic materials were studied, which laid the foundation for ultra-precision machining of IOL. Secondly, on the basis of the machining technology of IOL, the problems existed in the process are studied. The advantages and disadvantages of injection mould pressing, low temperature processing and normal temperature processing are described. The injection mould pressing method is more complicated, and the mold cost is high, and then the low temperature method is used to process IOL. The normal temperature processing method is developed from the low temperature processing method, and the glass transition temperature is adjusted to 10 鈩

本文編號(hào)：1855243