本文選題：生物相容性材料　切入點(diǎn)：周?chē)窠?jīng)　出處：《中國(guó)組織工程研究》2017年08期

【摘要】：背景:在周?chē)窠?jīng)修復(fù)方面,神經(jīng)導(dǎo)管已由傳統(tǒng)的無(wú)內(nèi)支架結(jié)構(gòu)逐步走向內(nèi)部結(jié)構(gòu)的創(chuàng)新,以構(gòu)建更加有利于周?chē)窠?jīng)再生的具有內(nèi)支架結(jié)構(gòu)的神經(jīng)導(dǎo)管。因此對(duì)于神經(jīng)導(dǎo)管內(nèi)部支架結(jié)構(gòu)的全面了解是十分必要的。目的:綜述近年來(lái)神經(jīng)導(dǎo)管內(nèi)支架在修復(fù)周?chē)窠?jīng)缺損方面的應(yīng)用。方法:以"nerve conduit/conduits/scaffolds/scaffold/channel/channels,internal scaffolds/scaffold,nerve regeneration/repair,hydrogel,acellularized/decellularized nerve"或"神經(jīng)導(dǎo)管,內(nèi)支架,周?chē)窠?jīng)修復(fù),凝膠,去細(xì)胞神經(jīng)"為檢索詞,應(yīng)用計(jì)算機(jī)分別在PubMed數(shù)據(jù)庫(kù)和中國(guó)知網(wǎng)、萬(wàn)方數(shù)據(jù)庫(kù)、中國(guó)生物醫(yī)學(xué)文獻(xiàn)數(shù)據(jù)庫(kù),檢索2009年1月至2015年12月與神經(jīng)導(dǎo)管內(nèi)支架相關(guān)的文章,對(duì)納入的47篇符合標(biāo)準(zhǔn)的文獻(xiàn)進(jìn)行綜述。結(jié)果與結(jié)論:具有內(nèi)支架結(jié)構(gòu)的神經(jīng)導(dǎo)管相較于傳統(tǒng)的無(wú)內(nèi)支架結(jié)構(gòu)的神經(jīng)導(dǎo)管在修復(fù)周?chē)窠?jīng)缺損方面有明顯優(yōu)勢(shì),可以更加有效的支持、引導(dǎo)和促進(jìn)周?chē)窠?jīng)的再生與功能的恢復(fù),有些神經(jīng)導(dǎo)管內(nèi)支架復(fù)合種子細(xì)胞、神經(jīng)營(yíng)養(yǎng)因子、細(xì)胞外基質(zhì)后修復(fù)效果更佳,甚至與自體神經(jīng)移植具有相似的修復(fù)效果。
[Abstract]:Background: in the area of peripheral nerve repair, the nerve conduit has gradually moved from the traditional non-stent structure to the internal structure innovation, in order to construct the nerve conduit with the stent structure which is more favorable to peripheral nerve regeneration.Therefore, it is necessary to have a comprehensive understanding of the internal stents of nerve ducts.Objective: to review the application of nerve catheter stent in repairing peripheral nerve defect in recent years.鏂規(guī)硶:浠，

本文編號(hào)：1711678