醫(yī)用二氧化碳吸收劑的制備工藝和產(chǎn)業(yè)化研究
發(fā)布時間:2018-03-31 02:24
本文選題:二氧化碳吸收劑 切入點:強度 出處:《浙江大學(xué)》2012年碩士論文
【摘要】:在臨床低流量封閉式麻醉系統(tǒng)中,需要有一種安全高效的二氧化碳吸收劑對病人呼吸產(chǎn)生的二氧化碳進(jìn)行及時快速的吸收。這種醫(yī)用二氧化碳吸收劑分為鈉石灰(鈉含量高于3wt%)和鈣石灰(鈉含量低于1wt%),前者會與麻醉系統(tǒng)中的麻醉劑發(fā)生毒性反應(yīng)生成有毒物質(zhì)CO和“化合物A”,但擁有很高的強度和吸收率。這里的強度是指產(chǎn)品放置一段時間后出現(xiàn)的粉塵的大小。后者與麻醉劑呈惰性,但是強度和吸收率略顯不足。目前國產(chǎn)的二氧化碳吸收劑強度低,吸收率也較低。 本文的主要工作是在研究出鈉石灰的配方和制備工藝后,并成功放大化實驗室制備方法并實現(xiàn)了產(chǎn)業(yè)化生產(chǎn),并使產(chǎn)品的性能與實驗室制備的試樣相比有了顯著的提升。 實驗結(jié)果表明:硅鋁酸鈉含量在4wt%左右時就能很好的起到增強劑的作用,繼續(xù)提高含量,產(chǎn)品強度基本不變而吸收率顯著下降。熱處理溫度增加,產(chǎn)品強度越好,熱處理在100-120℃處理5-15min時便可獲得理想的強度值。在產(chǎn)品中加入聚乙烯醇(2wt%)就能在基本不影響強度和吸收率的情況下有效防止產(chǎn)品出現(xiàn)粉化現(xiàn)象。 另外,本文還對鈣石灰進(jìn)行了初步的研究,實驗結(jié)果顯示再取代氫氧化鈉的物質(zhì)中,LiOH和三乙醇胺都基本能起到堿性劑的作用。 目前,鈉石灰已經(jīng)成功投入工業(yè)化生產(chǎn),擁有了年產(chǎn)千噸級,經(jīng)濟(jì)效益達(dá)百萬元級的鈉石灰生產(chǎn)線。
[Abstract]:In clinical low flow closed anesthesia systems, A safe and efficient carbon dioxide absorbent is needed for the rapid and timely absorption of carbon dioxide produced by the patient's breathing. This medical carbon dioxide absorbent is divided into sodium lime (sodium content higher than 3 wtts) and calcium lime (sodium content). Less than 1 wt. the former produces toxic substances CO and "compound A" by toxic reactions with anesthetics in the anesthetic system, but it has a high strength and absorptivity. The strength here refers to the dust that occurs after the product has been placed for a period of time. Size. The latter is inert with the anesthetic, However, the intensity and absorptivity of carbon dioxide absorbents are low and the absorptivity is low. The main work of this paper is to study the formulation and preparation process of sodium lime, and to amplify the laboratory preparation method and realize the industrial production successfully, and make the performance of the product obviously improved compared with the sample prepared in the laboratory. The experimental results show that the content of sodium aluminate can play a good role as an enhancer when the content of sodium silicate is about 4 wt%. The strength of the product is basically unchanged and the absorptivity is significantly decreased when the content of sodium silicate continues to increase. The higher the heat treatment temperature is, the better the strength of the product is. The ideal strength value can be obtained when 5-15min is treated at 100-120 鈩,
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