本文選題：微缺損　切入點(diǎn)：軟骨　出處：《醫(yī)用生物力學(xué)》2017年02期

【摘要】：目的研究軟骨在壓縮載荷作用下的損傷擴(kuò)展行為和演變機(jī)制。方法采用有限元方法建立微缺損的纖維增強(qiáng)多孔彈性的軟骨模型,對(duì)壓縮載荷作用下?lián)p傷演化過程進(jìn)行模擬和參數(shù)研究,獲得不同損傷擴(kuò)展階段軟骨基體和纖維的應(yīng)力、應(yīng)變分布規(guī)律。結(jié)果軟骨損傷表層和損傷前沿的應(yīng)變隨壓縮量的增大而顯著增大,兩者呈明顯的正相關(guān)性;在軟骨演化過程中同時(shí)存在向深層和左右兩側(cè)擴(kuò)展的趨勢(shì);軟骨中的裂紋和損傷優(yōu)先沿著纖維切線方向延伸,隨著損傷的加劇,軟骨橫向擴(kuò)展度明顯快于縱向擴(kuò)展速度。結(jié)論軟骨損傷演化過程與纖維的分布有著密切的關(guān)系,基質(zhì)和纖維的損傷相互促進(jìn),骨演化速度和程度在不同層區(qū)和不同階段存在變化。研究結(jié)果可為軟骨創(chuàng)傷性退變的預(yù)測(cè)及修復(fù)提供定性的參考,為臨床解釋損傷退變病理現(xiàn)象和治療提供理論依據(jù)。
[Abstract]:Objective to study the damage propagation behavior and evolution mechanism of cartilage under compression loading. The stress of cartilage matrix and fiber in different damage extension stages was obtained by simulating and studying the damage evolution process under compression loading. Results the strain of the surface layer and the front of the cartilage damage increased significantly with the increase of the compression amount, and the two strains showed a positive correlation, and there was a tendency to expand to the deep layer and the left and right sides during the evolution of the cartilage. The cracks and injuries in cartilage preferentially extend along the tangent direction of the fibers. With the increase of the injury, the degree of transverse expansion of cartilage is obviously faster than that of the longitudinal extension. Conclusion the evolution of cartilage injury is closely related to the distribution of fibers. The damage of matrix and fiber is mutually reinforcing, and the velocity and degree of bone evolution vary in different layers and stages. The results can provide a qualitative reference for the prediction and repair of traumatic degeneration of cartilage. To provide a theoretical basis for clinical interpretation of pathological phenomena and treatment of injury degeneration.
【作者單位】： 天津理工大學(xué)機(jī)械工程學(xué)院天津市先進(jìn)機(jī)電系統(tǒng)設(shè)計(jì)與智能控制重點(diǎn)實(shí)驗(yàn)室;
【基金】：國(guó)家自然科學(xué)基金項(xiàng)目(11402171,11372221,11432016)
【分類號(hào)】：R318.01;R68
，

本文編號(hào)：1682957