粉針劑間歇計(jì)量與連續(xù)充填裝置的協(xié)同設(shè)計(jì)
本文關(guān)鍵詞: 粉針劑 螺桿計(jì)量 連續(xù)充填 壓電振動(dòng) 協(xié)同設(shè)計(jì) 仿真分析 出處:《哈爾濱商業(yè)大學(xué)》2012年碩士論文 論文類型:學(xué)位論文
【摘要】:粉針劑分裝機(jī)是制藥行業(yè)的重要設(shè)備。由于分裝速度、精度與劑量變化適應(yīng)性等技術(shù)指標(biāo)均達(dá)不到國際領(lǐng)先水平,而且新產(chǎn)品開發(fā)周期長、設(shè)計(jì)手段落后,使得國產(chǎn)分裝機(jī)缺乏市場競爭力。因此,利用現(xiàn)代設(shè)計(jì)方法,對(duì)粉針劑分裝機(jī)的關(guān)鍵部件—計(jì)量與充填裝置進(jìn)行結(jié)構(gòu)與工作參數(shù)的協(xié)同設(shè)計(jì),顯得尤為關(guān)鍵,具有非�,F(xiàn)實(shí)的意義。 論文分析了粉針劑的物性,深入研究了粉針劑的流動(dòng)性、松裝密度等特性與分裝速度、分裝精度的關(guān)系,分析了粉狀物料的計(jì)量與充填方式,確定了基于間歇式螺桿計(jì)量、連續(xù)式壓電振動(dòng)充填的粉針劑計(jì)量充填研究方案,以克服粉針劑物性對(duì)分裝速度和精度的影響。 建立精密計(jì)量螺桿的數(shù)學(xué)模型,結(jié)合SolidWorks二次開發(fā)模塊和VB,建立了計(jì)量螺桿的參數(shù)化快速設(shè)計(jì)功能模塊。詳細(xì)設(shè)計(jì)計(jì)量螺桿、攪拌葉片與粉杯的結(jié)構(gòu)參數(shù),以改善傳統(tǒng)容積計(jì)量調(diào)節(jié)困難的缺陷。采用伺服電機(jī)直連計(jì)量螺桿的方式,精確控制螺桿的轉(zhuǎn)動(dòng),保證計(jì)量精度。 選用壓電雙晶片作為振動(dòng)驅(qū)動(dòng)源,合理設(shè)計(jì)了溜槽與板彈簧的結(jié)構(gòu)參數(shù),提出了此種振型固有頻率的計(jì)算方法,并擬定了粉針劑在輸送料盤上的理想運(yùn)動(dòng)過程,確定跳躍邊界條件。 采用壓電雙晶片驅(qū)動(dòng)的方式,設(shè)計(jì)了新型的粉料壓電振動(dòng)充填裝置;分析了粉針劑的振動(dòng)輸送與充填的機(jī)理,確定粉針劑振動(dòng)輸送邊界條件。提出機(jī)構(gòu)固有頻率的計(jì)算方法,優(yōu)化設(shè)計(jì)了溜槽與板彈簧的結(jié)構(gòu)參數(shù),以提高壓電振動(dòng)充填裝置性能。 深入分析了裝置計(jì)量與充填協(xié)同工作的工作原理,確定兩裝置在容積量與時(shí)間兩個(gè)方面的協(xié)同工作參數(shù),并以工作循環(huán)圖的方式表示整個(gè)計(jì)量充填周期的工作過程。利用SolidWorks軟件構(gòu)造計(jì)量與充填裝置的三維模型,結(jié)合COSMOS Motion模塊進(jìn)行運(yùn)動(dòng)學(xué)仿真,確定了裝置的最佳工作參數(shù),并輸出相應(yīng)的曲線,得出了系統(tǒng)達(dá)到最大充填速度的振動(dòng)頻率為10Hz,振動(dòng)送料器的最大旋轉(zhuǎn)速度為7.95rad/s。此外,還對(duì)板彈簧做了力學(xué)分析,驗(yàn)證模型的合理性和可行性。
[Abstract]:Powder dispensing machine is an important equipment in the pharmaceutical industry. Due to the technical indexes such as speed, accuracy and adaptability of dosage change, it can not reach the international leading level, and the new product development cycle is long, and the design means lag behind. Therefore, it is very important to use modern design method to design the structure and working parameters of the key parts of powder dispenser, metering and filling device. Has very realistic significance. In this paper, the physical properties of the powder injection are analyzed, and the relationship between the fluidity and the loose density of the powder injection and the speed and precision of the powder injection is studied. The metering and filling method of the powder material is analyzed, and the metering method based on the intermittent screw is determined. In order to overcome the influence of the physical properties of powder injection on the speed and accuracy of split filling, the research scheme of continuous piezoelectric vibration filling is presented in this paper. The mathematical model of precision measuring screw was established. The parameterized and rapid design function module of metering screw was established with the combination of SolidWorks secondary development module and VB. The structural parameters of metering screw, agitating blade and powder cup were designed in detail. In order to improve the defects of the traditional volume measurement adjustment, the servo motor is directly connected with the measuring screw to accurately control the screw rotation and ensure the measurement accuracy. The piezoelectric bimorph is chosen as the vibration driving source, the structural parameters of the chute and plate spring are reasonably designed, the calculation method of the natural frequency of the vibration mode is put forward, and the ideal movement process of the powder injection on the conveying plate is worked out. Determine the jump boundary conditions. A new type of piezoelectric vibration filling device is designed by using piezoelectric bimorph drive, the mechanism of vibrating conveying and filling of powder injection is analyzed, the boundary condition of vibrating conveying of powder injection is determined, and the method of calculating the natural frequency of mechanism is put forward. The structural parameters of chute and plate spring are optimized to improve the performance of piezoelectric vibration filling device. The working principle of cooperative work between metering and filling is deeply analyzed, and the cooperative working parameters of the two devices in volume and time are determined. The working process of the whole metering and filling cycle is represented by the working cycle diagram. The 3D model of the metering and filling device is constructed by using SolidWorks software, and the kinematics simulation is carried out with the COSMOS Motion module, and the optimum working parameters of the device are determined. The corresponding curves are outputted, the vibration frequency of the system reaching the maximum filling speed is 10 Hz and the maximum rotating velocity of the vibrating feeder is 7.95 radr / s. In addition, the mechanical analysis of the plate spring is done to verify the rationality and feasibility of the model.
【學(xué)位授予單位】:哈爾濱商業(yè)大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2012
【分類號(hào)】:TH788;TP391.72
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