7年間鄭州市某院住院患者藥疹發(fā)生率和相關(guān)危險因素分析
[Abstract]:Objective to investigate the characteristics and related risk factors of the incidence of traditional Chinese medicine rash in inpatients in our hospital in recent 7 years. Methods 143262 hospitalized patients from January 2006 to December 2012 were analyzed retrospectively. among them, 280 patients with drug rash were consulted by dermatologists. The annual incidence of drug rash was divided into two groups. The classification of drugs causing drug eruption and the characteristics of drug eruption department. Results the average age of 280 patients with drug eruption was (37.23 鹵15.68) years old. The incidence of drug eruption from 2006 to 2012 was 1.04, 1.17, 1.61, 2.41, 2.59, 2.68, 1.95, respectively, and the incidence of drug eruption decreased in 2012. Among the sensitizing drugs, antibiotics accounted for 43.5%, antipyretic and analgesic drugs and non-steroidal anti-inflammatory drugs accounted for 14.29%, antiepileptic drugs accounted for 12.50%, traditional Chinese medicine preparations accounted for 12.14%, and biological products accounted for 10.71%. The incidence of drug eruption in internal medicine system was significantly higher than that in surgical system, especially in neurology department (17.50%) and respiratory department (5.56%). Conclusion the incidence of drug rash caused by antibiotics decreased in 2012. However, antibiotics, antipyretic and analgesic drugs and non-steroidal anti-inflammatory drugs still ranked first and second. The rash caused by traditional Chinese medicine preparation and biological products is increasing year by year, which should be paid enough attention by clinicians.
【作者單位】: 鄭州大學(xué)第五附屬醫(yī)院醫(yī)院皮膚性病科;
【分類號】:R758.25
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