腦血管型神經(jīng)梅毒的臨床及影像學(xué)特點(diǎn)
[Abstract]:Objective: to investigate the clinical and imaging features of cerebrovascular neurosyphilis. Methods: serum and cerebrospinal fluid Treponema pallidum agglutination test (TPHA) and rapid plasma antibody test (RPR) were performed in 23 patients with cerebrovascular neurosyphilis by enzyme linked immunosorbent assay (Elisa). The clinical data, especially the cephalic imaging findings, were analyzed. Results: among the 23 patients, 8 (34.8%) had progressive stroke, 3 (13.0%) had transient ischemic attack and 3 (13.0%) had a history of cerebral infarction. Serum TPHA and RPR were positive in all the patients with the titer range of 1: 4: 128, TPHA and RPR in cerebrospinal fluid were positive, the titer was 1: 2 or 1: 64, with or without the increase of cell number and protein. Cranial MRI suggested that intracranial single or multiple infarct lesions were associated with cerebral atrophy and white matter demyelination, and intracranial vascular stenosis could be found by CTA. Conclusion: the rate of progression and recurrence of neurosyphilis of cerebrovascular type is high, multiple lesions can be found on cranial image, and multiple stenosis of large and middle artery can be found in vascular image, and the probability of cerebral atrophy is higher. Syphilis should be detected routinely in patients with ischemic stroke, especially when there are no related risk factors such as arteriosclerosis and cardiogenic stroke.
【作者單位】: 浙江省湖州市中心醫(yī)院神經(jīng)內(nèi)科;
【分類號(hào)】:R759.13
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