【摘要】：目的探討潤燥止癢膠囊口服聯(lián)合鹵米松軟膏局部外用治療原發(fā)性皮膚淀粉樣變病的臨床療效及安全性。方法將就診于門診的129例原發(fā)性皮膚淀粉樣變病患者隨機分為治療組及對照組,其中治療組68例給予潤燥止癢膠囊口服及鹵米松軟膏局部外用;對照組61例,僅給予鹵米松外用治療。分別在治療第2,4和8周末時進行癥狀評分、療效判定和安全性評價。結果在治療的第2周末時,治療組和對照組有效率分別為47.06%和45.90%,兩組差異無統(tǒng)計學意義(P0.05);在治療的第4和第8周末時,治療組有效率為69.12%和83.82%,對照組為55.74%和62.30%,兩組差異均有統(tǒng)計學意義(P0.05)。兩組患者僅有輕微不良反應。結論潤燥止癢膠囊口服聯(lián)合鹵米松軟膏局部外用治療原發(fā)性皮膚淀粉樣變病臨床療效較好,中長期使用(1~2個月)療效優(yōu)于單用鹵米松治療,且不良反應輕微。
[Abstract]:Objective to investigate the clinical efficacy and safety of Runzao Zhiyang capsule combined with halomethasone ointment in the treatment of primary cutaneous amyloidosis. Methods 129 patients with primary cutaneous amyloidosis were randomly divided into treatment group and control group. 68 patients in treatment group were given Runzao Zhiyang capsule and halomisone ointment for topical use. The control group (61 cases) was treated with halomethasone for external use only. Symptom scores, efficacy and safety were evaluated at the end of the 4th and 8th week of treatment. Results at the end of the second week of treatment, the effective rates of the treatment group and the control group were 47.06% and 45.90%, respectively. There was no significant difference between the two groups (P0.05). At the end of the 4th and 8th week, the effective rate of the treatment group was 69.12% and 83.82%, the control group was 55.74% and 62.30%, the difference between the two groups was statistically significant (P0.05). There were only minor adverse reactions in both groups. Conclusion the clinical efficacy of Runzao Zhiyang capsule combined with halomethasone ointment in treating primary cutaneous amyloidosis is better than that of halomethasone alone in the long term (1 ~ 2 months), and the adverse reaction is slight.
【作者單位】： 西寧市第二人民醫(yī)院;
【分類號】：R758.6

【相似文獻】

相關期刊論文 前10條

1 龐曉文;董朝暉;;氟芬那酸丁酯軟膏治療原發(fā)性皮膚淀粉樣變病療效觀察[J];中國麻風皮膚病雜志;2007年07期

2 王明悅;陳璨;張凡;陳喜雪;涂平;朱學駿;;無明顯內(nèi)臟損害的原發(fā)性系統(tǒng)性淀粉樣變病2例[J];中國皮膚性病學雜志;2010年12期

3 潘然;彭美雄;徐宏俊;陳周;杜娟;徐前喜;戴林;張建中;;原發(fā)性系統(tǒng)性淀粉樣變病1例[J];中國皮膚性病學雜志;2012年06期

4 Stewart W D;王洪琛;;原發(fā)性苔蘚性皮膚淀粉樣變病[J];國外醫(yī)學.皮膚病學分冊;1982年04期

5 尚元元;丁文清;;維A酸類藥物聯(lián)合苦參素治療原發(fā)性皮膚淀粉樣變病22例臨床觀察[J];臨床皮膚科雜志;2006年09期

6 譚燃景;郝進;;原發(fā)性皮膚淀粉樣變病的病因及發(fā)病機制[J];醫(yī)學臨床研究;2007年10期

7 李丹,陳明春;皮膚異色病樣淀粉樣變病1例[J];臨床皮膚科雜志;2005年06期

8 張敏;何勤;余德厚;陸洪光;龍義國;廖躍;;以皮疹為首發(fā)表現(xiàn)的原發(fā)性系統(tǒng)性淀粉樣變病1例[J];中國皮膚性病學雜志;2010年05期

9 朱林學;陳紅英;陳龍;;皮膚異色病樣淀粉樣變病2例[J];臨床皮膚科雜志;2006年02期

10 陳s，

本文編號：2344331