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放射性皮炎防治機制及措施研究

發(fā)布時間:2018-10-13 09:42
【摘要】:正放射治療(以下簡稱"放療")是治療惡性腫瘤的主要治療手段之一。60%的惡性腫瘤患者在治療的不同階段需要接受放療。隨著射線劑量的增加,射線不僅對腫瘤組織產(chǎn)生殺傷作用,還引起照射部位放射性皮炎,這是腫瘤放療中最常見的并發(fā)癥之一[1]。究其原因,除了射線本身的物理特性之外,同步化學(xué)藥物治療(化療)、靶向藥物和面罩固定等應(yīng)用也是增加皮膚毒性的重要因素[2-3],如Ⅲ~Ⅳ期頭頸部腫瘤患者行同步放療和化療(照射劑量≥66~70 Gy,化療≥6
[Abstract]:Positive radiotherapy (hereinafter referred to as "radiotherapy") is one of the main treatment methods for malignant tumors. 60% of patients with malignant tumors need radiotherapy at different stages of treatment. With the increase of radiation dose, radiation not only can kill tumor tissue, but also cause radiation dermatitis. This is one of the most common complications in tumor radiotherapy [1]. The reason is that in addition to the physical properties of the ray itself, Simultaneous chemotherapeutic therapy (chemotherapy), targeted drugs and mask fixation are also important factors in increasing skin toxicity [2-3], such as concurrent radiotherapy and chemotherapy (radiation dose 鈮,

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