本文選題：Rosai-Dorfman病 + 混合型　； 參考：《臨床皮膚科雜志》2016年05期

【摘要】：報(bào)告1例混合型Rosai-Dorfman病。患兒男,12歲。因上眼瞼皮下腫塊1年,術(shù)后復(fù)發(fā)1個(gè)月就診。皮膚科檢查:雙側(cè)上眼瞼、腮部、頜下外側(cè)皮下均可觸及腫塊,大小不規(guī)則,直徑3~5 cm不等,質(zhì)軟,邊界清,無(wú)壓痛,表面皮膚完整。左頜下腫物組織病理檢查:左頜下淋巴結(jié)良性病變,大部分組織細(xì)胞瘤樣增生伴淋巴竇結(jié)構(gòu)消失,部分增大的組織細(xì)胞胞質(zhì)內(nèi)可見淋巴細(xì)胞及中性粒細(xì)胞。免疫組化檢查:瘤樣增生的組織細(xì)胞S-100蛋白(+)、CD163(+)、CD68(散在弱+)、CD1α(-)。診斷:混合型Rosai-Dorfman病。
[Abstract]:A case of mixed Rosai-Dorfman 's disease was reported. The boy was 12 years old. Because of the upper eyelid subcutaneous mass for 1 year, recurrence 1 month after treatment. Dermatology examination: bilateral upper eyelids, cheeks, subcutaneous submandibular can touch the mass, the size is irregular, the diameter varies from 3 to 5 cm, the quality is soft, the boundary is clear, there is no tenderness, the surface skin is intact. Histopathological examination of left submaxillary tumor: benign lesions of left submaxillary lymph node, most histiocytoma-like hyperplasia with disappearance of lymphatic sinus structure, lymphocyte and neutrophils in some enlarged histiocytic cytoplasm. Immunohistochemical examination showed that S-100 protein was present in tumor-like proliferative histiocytes. Diagnosis: mixed Rosai-Dorfman disease.
【作者單位】： 華中科技大學(xué)同濟(jì)醫(yī)學(xué)院附屬同濟(jì)醫(yī)院皮膚科;
【分類號(hào)】：R758.6

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1 閻曉玲;;Rosai-Dorfman病[J];中國(guó)現(xiàn)代神經(jīng)疾病雜志;2014年06期

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