本文選題：嬰兒 + 特應(yīng)性皮炎�。� 參考：《遼寧中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：目的:探討1-12月齡特應(yīng)性皮炎(AD)嬰兒發(fā)病的相關(guān)因素,為預(yù)防和控制AD提供臨床依據(jù)。材料與方法:選取2015年1月至2016年1月在解放軍第202醫(yī)院過敏反應(yīng)科門診就診的1-12月齡AD嬰兒126例納入研究組,同一時期在幼兒保健科隨機(jī)選取1-12月齡健康嬰兒142例納入對照組。本次研究通過填寫調(diào)查問卷的方式進(jìn)行,對家族史、母親妊娠年齡、生產(chǎn)方式、喂養(yǎng)方式、添加輔食時間、室內(nèi)吸煙、飼養(yǎng)寵物情況7個因素進(jìn)行卡方檢驗,分析AD發(fā)病的相關(guān)因素,對相關(guān)因素進(jìn)行多因素Logistic回歸分析,分析各因素與AD發(fā)病的相關(guān)性。結(jié)果:1.研究組126例特應(yīng)性皮炎患兒,其中男嬰71例,占56.35%,女嬰55例,占43.65%;對照組142例健康嬰兒,其中男嬰79例,占55.63%,女嬰63例,占44.37%。經(jīng)卡方檢驗χ2=0.014,P=0.906,在性別上兩組之間沒有統(tǒng)計學(xué)差異。2.在相關(guān)因素分析中,研究自身因素與AD發(fā)病的關(guān)系,經(jīng)卡方檢驗家族史χ2=35.165,P=0.000,母親妊娠年齡χ2=0.003,P=0.959,生產(chǎn)方式χ2=28.711,P=0.000,喂養(yǎng)方式χ2=7.436,P=0.024,添加輔食時間χ2=0.212,P=0.645,其中家族史、生產(chǎn)方式、喂養(yǎng)方式有統(tǒng)計學(xué)意義。3.研究環(huán)境因素與AD發(fā)病的關(guān)系,經(jīng)卡方檢驗吸煙環(huán)境χ2=11.955,P=0.001,飼養(yǎng)寵物χ2=6.080,P=0.014,吸煙環(huán)境和飼養(yǎng)寵物有統(tǒng)計學(xué)意義。4.對相關(guān)因素進(jìn)行多因素Logistic回歸分析,結(jié)果表明家族史(OR=7.105)和生產(chǎn)方式(0R=6.771)與AD發(fā)病相關(guān)性最強(qiáng)。結(jié)論:1.自身因素中家族史、生產(chǎn)方式、喂養(yǎng)方式為1-12月齡嬰兒AD發(fā)病的相關(guān)因素。2.環(huán)境因素中吸煙環(huán)境、飼養(yǎng)寵物為1-12月齡嬰兒AD發(fā)病的相關(guān)因素。3.家族史和生產(chǎn)方式為1-12月齡嬰兒AD發(fā)病的主要相關(guān)因素。
[Abstract]:Objective: to investigate the risk factors of AD in infants aged from 1 to 12 months old, and to provide clinical basis for prevention and control of AD. Materials and methods: 126 AD infants aged from 1 to 12 months from January 2015 to January 2016 were enrolled in the study group. In the same period, 142 healthy infants aged 1 to 12 months were randomly selected into the control group. This study was conducted by filling out a questionnaire to examine seven factors, including family history, maternal pregnancy age, mode of production, feeding method, supplementary feeding time, indoor smoking, pet keeping, etc. The related factors of AD were analyzed, and multivariate Logistic regression analysis was carried out to analyze the correlation between each factor and AD. The result is 1: 1. There were 126 cases of atopic dermatitis in the study group, including 71 cases of male infants (56.35%), 55 cases of female infants (43.65%), 142 cases of healthy infants in control group, 79 cases of male infants (55.63%) and 63 cases of female infants (44.37%). The chi-square test showed that there was no statistical difference between the two groups. In the analysis of related factors, the authors studied the relationship between their own factors and the incidence of AD. By chi-square test, the family history was 蠂 2 235. 165% P0. 000, the maternal gestational age 蠂 2 0. 003 + P0. 959, the mode of production 蠂 228. 711 P0. 000, the feeding mode 蠂 2 + 7. 436 P0. 024, and the supplementary feeding time 蠂 2 + 0. 212 P0. 645. Among them, the family history, the production mode, the mode of production, Feeding mode has statistical significance. In order to study the relationship between environmental factors and AD, the smoking environment 蠂 ~ 2 ~ 2 ~ (11) 95 ~ (5) P ~ + 0.001, and keeping pets 蠂 ~ (2) 6.080 (P ~ (0.014) were tested by chi-square test. There was statistically significant difference between smoking environment and keeping pets (P ~ (0.014). Multivariate Logistic regression analysis showed that the family history was 7.105) and the mode of production was 6.771). Conclusion 1. The family history, mode of production and feeding mode were related factors of AD in infants aged 1 to 12 months. Among the environmental factors, smoking and keeping pets were related factors of AD incidence in infants aged 1 to 12 months. Family history and mode of production were the main related factors of AD in infants aged 1-12 months.
【學(xué)位授予單位】：遼寧中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2016
【分類號】：R758.2
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本文編號：1890171