本文選題：皮膚 + 護膚霜��； 參考：《中國礦業(yè)大學(xué)》2010年博士論文

【摘要】： 皮膚宏觀摩擦學(xué)研究有效的模擬了現(xiàn)實生活中皮膚與各種物體表面的接觸,有重要的現(xiàn)實意義,而皮膚納米摩擦學(xué)研究在納米尺度上深入研究皮膚的表面微觀組織結(jié)構(gòu),以及皮膚與相對運動表面在接觸界面上分子間的相互作用,兩者相互結(jié)合,有助于建立完善的皮膚摩擦學(xué)理論。同時研究表皮-護膚霜分子之間的相互作用,對于開發(fā)高效的護膚品具有重要意義。 本文以大鼠表皮、人造皮膚和人體皮膚為研究對象,使用原子力顯微鏡(AFM)和納米壓痕儀研究了大鼠表皮(簡稱表皮)和護膚霜涂覆表皮(簡稱涂覆表皮)的納米力學(xué)性能、摩擦性能和摩擦電性能,研究了人造皮膚的納米摩擦性能,使用往復(fù)摩擦試驗機研究了宏觀尺度下表皮和涂覆表皮的摩擦性能,使用UMT-2多功能摩擦磨損試驗機研究了人手皮膚和護手霜涂覆人手皮膚的摩擦性能、人體皮膚和紡織品之間的摩擦性能,主要結(jié)論如下: 大鼠表皮的納米力學(xué)性能試驗研究顯示,表皮和涂覆表皮的表面劃痕深度隨著載荷的增加而增大;當(dāng)載荷小于15μN時,涂覆表皮具有較好的抗擦傷性;護膚霜可以有效的軟化皮膚,增加皮膚的彈性和延展性,降低皮膚角質(zhì)層碎片的產(chǎn)生。 大鼠表皮的納米摩擦學(xué)性能研究顯示,護膚霜能夠降低表皮的粗糙度并且提高表皮的親水性;表皮的摩擦系數(shù)和粘著力隨著膜厚、速度和載荷的變化而變化;環(huán)境濕度和溫度顯著影響表皮的摩擦系數(shù)和粘著力;由于表面膜厚的變化,表皮和涂覆表皮的摩擦系數(shù)和粘著力隨著掃描周期的變化而變化。 大鼠表皮的納米摩擦電特性研究顯示,環(huán)境中的水分和護膚霜可以有效的消除表皮的靜電荷。皮膚上的摩擦靜電荷通過與周圍空氣的接觸而衰減;表皮在摩擦過程中容易產(chǎn)生靜電,而護膚品能夠很好的抑制摩擦電荷的產(chǎn)生;當(dāng)采用宏觀尺度方法摩擦表皮時,絕對電勢的變化大于納米尺度摩擦方法;表皮和涂覆表皮的表面絕對電勢的變化量隨著速度、載荷和摩擦?xí)r間的增大而增大。 護膚霜對大鼠表皮納米摩擦學(xué)性能的影響研究顯示,純羊毛脂和純凡士林具有較好的持久性,質(zhì)地粘著油膩。無油護膚霜和普通護膚霜的持久性相對較低,質(zhì)地潤滑。水合甘油的持久性最差,質(zhì)地潤滑;高動態(tài)粘度的護膚霜的持久性較好,同時會使表皮產(chǎn)生高的摩擦系數(shù)。環(huán)境濕度對五種涂覆表皮的粘著和力學(xué)性能影響的研究顯示,環(huán)境濕度影響表皮的表面膜厚、粘著力和彈性模量。 人造皮膚的納米摩擦學(xué)性能研究顯示,人造皮膚具有和大鼠表皮相似的表面性能和摩擦性能,是大鼠表皮的適當(dāng)替代物;由于人造皮膚-2的硬度和大鼠表皮相似,人造皮膚-2比人造皮膚-1更適合作為大鼠表皮的替代物使用;當(dāng)涂覆護膚品后,人造皮膚顯示出和大鼠表皮相似的表面、摩擦和力學(xué)性能變化,因此在護膚品研究中適合作為大鼠表皮的替代物使用。 大鼠表皮的宏觀摩擦學(xué)性能研究顯示,表皮和涂覆表皮的摩擦學(xué)性能對尺度有依賴性。宏觀尺度下測得皮膚摩擦系數(shù)大于納米尺度下測得的。不同研究尺度下,護膚霜膜厚、速度和載荷對表皮和涂覆表皮摩擦性質(zhì)的影響有一定差異,表皮和涂覆表皮的磨損性能有一定的差異。 人體皮膚的宏觀摩擦性能試驗研究顯示,皮膚濕度和溫度顯著影響皮膚的摩擦性能;人體手部皮膚的摩擦性能研究表明,人體手部四個部位皮膚的摩擦系數(shù)的從高到低依次為指紋,手掌,手背和指甲;護手霜涂覆皮膚的摩擦性能研究表明,甘油護手霜的潤膚效果最明顯,凡士林護手霜和普通護手霜的潤膚效果相近。凡士林護手霜的保持效果最佳,甘油護手霜和普通護手霜的保持效果相近;皮膚-紡織品的摩擦性能研究表明,四種紡織品的摩擦系數(shù)由高到低分別為毛呢,皮革,絲綢和棉布。
[Abstract]:The study of skin macrotribology effectively simulates the contact between the skin and the surface of various objects in real life, and it has important practical significance. The skin nano tribological study studies the microstructure of the skin surface and the interaction between the skin and the relative motion surface at the contact interface. Combining with each other helps to establish a perfect theory of skin tribology. At the same time, it is of great significance to study the interaction between skin cream molecules and to develop efficient skin care products.
In this paper, the nanomechanical properties, friction properties and friction electrical properties of rat epidermis (abbreviated epidermis) and skin cream coated epidermis were studied by atomic force microscope (AFM) and nano indentation instrument, and the friction properties of the artificial skin were studied. The friction test machine was used to study the friction properties of the epidermis and the coated epidermis on the macro scale. The friction performance of human hand skin and hand cream coated hand skin and the friction properties between human skin and textiles were studied by the UMT-2 multi-function friction and wear tester. The main conclusions are as follows:
The experimental study on the nanomechanical properties of the rat epidermis shows that the surface scratch depth of the epidermis and the coated epidermis increases with the increase of the load. When the load is less than 15 mu N, the coating epidermis has better abrasion resistance; the skin cream can effectively soften the skin, increase the elasticity and ductility of the skin, and reduce the production of the cuticle fragments.
The study of the nano tribological properties of the rat epidermis shows that the skin cream can reduce the roughness of the epidermis and improve the hydrophilicity of the epidermis. The friction coefficient and adhesion of the epidermis vary with the change of the thickness of the membrane, the velocity and the load, and the environmental humidity and temperature influence the friction coefficient and adhesion of the epidermis. The friction coefficient and adhesive force of skin and coated skin change with the change of scanning period.
The study of the nano friction electrical properties of the rat epidermis shows that the water and skin cream in the environment can effectively eliminate the static charge of the epidermis. The friction static charge on the skin attenuates through contact with the surrounding air; the epidermis can easily produce static electricity during the friction process, and the skin care product can inhibit the generation of the friction charge well; when adopting the macro When the scale method friction the epidermis, the change of absolute potential is greater than that of the nano scale friction method, and the change of surface absolute potential of the epidermis and the coated epidermis increases with the increase of velocity, load and friction time.
The effect of skin cream on the skin nano tribological properties of rats showed that pure lanolin and pure Vaseline had better durability, the texture was greasy, the durability of oil free skin cream and ordinary skin cream was relatively low, the texture was lubricated. The durability of hydrated glycerol was the worst, the texture was lubricated, and the persistence of high dynamic viscosity cream was better. The effect of ambient humidity on the adhesion and mechanical properties of the five coated epidermis shows that the ambient humidity affects the surface film thickness, adhesion and modulus of elasticity of the epidermis.
The study of nano tribological properties of artificial skin shows that artificial skin has similar surface and frictional properties with rat epidermis, which is the appropriate substitute for rat epidermis. Because the hardness of artificial skin -2 is similar to that of rat skin, artificial skin -2 is more suitable to be used as a substitute for rat epidermis than that of artificial skin -1; when coating skin care products, the artificial skin is used as a skin care product. After that, the artificial skin shows the surface, friction and mechanical properties of the rat's epidermis, so it is suitable to be used as a substitute for the skin of the rat in the skin care research.
The study of the macro tribological properties of the epidermis of rats showed that the tribological properties of the epidermis and the coated epidermis were dependent on the scale. The skin friction coefficient measured at the macro scale was greater than that measured in the nanoscale. The effect of skin cream thickness, velocity and load on the skin and the coating skin friction properties under different scale were different. The wear properties of the skin and the coating are different.
The experimental study on the macro friction performance of human skin showed that the skin humidity and temperature significantly affected the skin's friction performance, and the friction performance of the human hand skin showed that the friction coefficient of the skin of the four parts of the human hand from high to low was the fingerprint, the palm, the hand back and the nail, and the friction performance of the hand cream coated skin. The moisturizing effect of glycerol hand cream is the most obvious, Vaseline hand cream and ordinary hand cream are similar. The Vaseline hand cream is the best, the glycerol hand cream and the ordinary hand cream keep the same effect; the friction properties of the skin textiles show that the friction coefficient of the four kinds of textiles is from high to low, respectively. Leather, silk and cotton.

【學(xué)位授予單位】：中國礦業(yè)大學(xué)
【學(xué)位級別】：博士
【學(xué)位授予年份】：2010
【分類號】：R751

【引證文獻】

相關(guān)碩士學(xué)位論文 前1條

1 李巖;仿生醫(yī)用針頭穿刺阻力變化特性研究[D];吉林大學(xué);2011年

，

本文編號：1836008