本文選題：嬰兒血管瘤 + 環(huán)境因素��； 參考：《臨床皮膚科雜志》2014年08期

【摘要】：目的:探討嬰兒血管瘤發(fā)病的環(huán)境危險因素。方法:2010年5月2012年12月,上海交通大學(xué)醫(yī)學(xué)院附屬新華醫(yī)院皮膚科門診收集年齡≤12個月的嬰兒血管瘤患者及健康對照各936例。對其父母進(jìn)行面對面訪談式問卷調(diào)查,內(nèi)容包括孕前1年內(nèi)和(或)孕期父母的一般情況及可能的環(huán)境危險因素。運(yùn)用Logistic模型對數(shù)據(jù)進(jìn)行單因素和多因素回歸分析疾病的危險因素,計算比值比和95%可信區(qū)間。結(jié)果:單因素回歸分析篩選出嬰兒血管瘤發(fā)生的危險因素共9個。多因素回歸分析顯示父親職業(yè)暴露油漆涂料(OR=2.223,95%CI:1.366~3.620)、汽油柴油(0R=1.719,95%CI:1.096~2.698)、化肥農(nóng)藥(OR=2.511,95%CI:1.546~4.079),和母親職業(yè)暴露化肥農(nóng)藥(OR=2.042,95%CI:1.349~3.094)、皮革塑料粘合劑(OR=3.371,95%CI:2.030~5.596),母親服用營養(yǎng)滋補(bǔ)品(OR=1.412,95%CI:1.057~1.889)、醫(yī)師處方保胎藥(OR=11.534,95%CI:7.990~16.651),以及父母居室方圓500米內(nèi)有化工企業(yè)和(或)染料印刷企業(yè)(OR=2.197,95%CI:1.398~3.455)均是嬰兒發(fā)生血管瘤的危險因素。結(jié)論:嬰兒血管瘤的發(fā)生與父母孕前1年內(nèi)和(或)孕期某些環(huán)境因素(主要是環(huán)境雌激素)的暴露相關(guān)。
[Abstract]:Objective: to investigate the environmental risk factors of infantile hemangioma. Methods: 936 cases of infantile hemangioma and 936 healthy controls were collected from Department of Dermatology, Xinhua Hospital affiliated to Shanghai Jiaotong University Medical College in May, 2010. Face-to-face interviews were conducted on their parents, including the general situation and possible environmental risk factors of their parents during 1 year before pregnancy and / or during pregnancy. Logistic model was used to analyze the risk factors of disease by univariate and multivariate regression. The ratio ratio and 95% confidence interval were calculated. Results: nine risk factors of infantile hemangioma were screened by single factor regression analysis. 澶氬洜绱犲洖褰掑垎鏋愭樉紺虹埗浜茶亴涓氭毚闇叉補(bǔ)婕嗘秱鏂，

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