本文關(guān)鍵詞： 銀屑病 內(nèi)皮素 精神因素 青海地區(qū)　出處：《臨床皮膚科雜志》2016年03期 　論文類型：期刊論文

【摘要】：正2010年流行病學(xué)調(diào)查研究顯示,我國(guó)銀屑病患病率為0.47%[1],全國(guó)銀屑病患者已逾300萬[2]。國(guó)外學(xué)者曾報(bào)告1例因在戰(zhàn)爭(zhēng)中經(jīng)歷悲痛而于6個(gè)月后發(fā)病的銀屑病患者,認(rèn)為其精神心理上的抑郁為本病的誘發(fā)因素[3]。內(nèi)皮素(ET)是迄今發(fā)現(xiàn)的最強(qiáng)的長(zhǎng)效縮血管活性物質(zhì),精神緊張、組織缺氧、機(jī)體氧化代謝增強(qiáng)及兒茶酚胺水平增高等均可刺激前內(nèi)皮素原的轉(zhuǎn)錄,促進(jìn)ET的合成和釋放,其作用時(shí)間持久,不為受體及5-羥
[Abstract]:Epidemiological investigation in 2010 showed that the prevalence rate of psoriasis in China was 0.47%, and the number of psoriasis patients in China had exceeded 3 million. Foreign scholars reported a patient with psoriasis who had developed after 6 months because of his grief in the war. It is considered that depression in mental and psychological state is the predisposing factor of this disease [3] .Endothelin et is the strongest long-acting vasoconstrictive active substance found so far. The enhancement of oxidative metabolism and the increase of catecholamine level can stimulate the transcription of proendothelin and promote the synthesis and release of et.
【作者單位】： 青島市第三人民醫(yī)院皮膚科;青海大學(xué)附屬醫(yī)院皮膚科;
【分類號(hào)】：R758.63
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本文編號(hào)：1517421