【摘要】：目的:研究MRI、~(99m)锝-甲氧基異丁基異腈(~(99m)Tc-MIBI)核素顯像及彩色多普勒超聲等3種影像學(xué)聯(lián)用在繼發(fā)性甲狀旁腺功能亢進(jìn)癥(SHPT)術(shù)前定位的診斷價值。方法:回顧性分析2010-2017年期間首次行甲狀旁腺切除術(shù)的72例SHPT患者,72例患者均通過上述3種影像學(xué)對病變甲狀旁腺進(jìn)行術(shù)前定位。以手術(shù)后病理診斷結(jié)果為金標(biāo)準(zhǔn),分別統(tǒng)計出3種影像學(xué)檢查聯(lián)用及各自所診斷甲狀旁腺的確診數(shù)及誤診數(shù),并計算敏感度及特異度,通過SPSS 19.0軟件運用率的χ~2檢驗將3種影像學(xué)檢查聯(lián)用同每種影像學(xué)方法的敏感度及特異度分別加以對比分析。結(jié)果:術(shù)后病理所報甲狀旁腺共282枚,MRI、~(99m)Tc-MIBI核素顯像、彩色多普勒超聲及3種影像學(xué)檢查聯(lián)用的敏感度分別為72.70%、47.52%、44.33%、82.27%;特異度分別為78.16%、91.75%、95.14%、67.96%;3種影像學(xué)聯(lián)用的敏感度大于各自的敏感度,均差異有統(tǒng)計學(xué)意義,而3種影像學(xué)聯(lián)用的特異度均小于各自的特異度,差異有統(tǒng)計學(xué)意義。結(jié)論:MRI、~(99m)Tc-MIBI核素顯像及彩色多普勒超聲等3種影像學(xué)檢查聯(lián)用對病變甲狀旁腺術(shù)前定位的診斷價值較高,可有效輔助SHPT的手術(shù)治療。
[Abstract]:Objective: to study the diagnostic value of MRI,~ _ (99m) technetium-methoxyisobutylisonitrile (~ (99m) Tc-MIBI) radionuclide imaging and color Doppler ultrasound in the preoperative localization of secondary hyperparathyropathy (SHPT). Methods: 72 patients with SHPT who underwent parathyroidectomy for the first time from 2010 to 2017 were analyzed retrospectively. the preoperative localization of parathyroidectomy was performed in 72 patients with parathyroidectomy. According to the results of pathological diagnosis after operation as the gold standard, the number of diagnosis and misdiagnosis of parathyroid gland were counted, and the sensitivity and specificity were calculated. The sensitivity and specificity of the three imaging examinations combined with each imaging method were compared and analyzed by the Chi ~ 2 test of the operation rate of SPSS 19.0 software. The sensitivity and specificity of the three imaging examinations were compared with those of each imaging method, and the sensitivity and specificity of each imaging method were compared and analyzed by means of the Chi ~ 2 test of the operation rate of the three imaging examinations. Results: the sensitivity, specificity, specificity and specificity of MRI,~ (99m) Tc-MIBI radionuclide imaging, color Doppler ultrasound and three kinds of imaging were 72.70%, 47.52%, 44.33%, 82.27%, 78.16%, 91.75%, 95.14% and 67.96%, respectively. the sensitivity, specificity, specificity and specificity were 72.70%, 47.52%, 44.33%, 82.27%, 78.16%, 91.75%, 95.14% and 67.96%, respectively. The sensitivity of the three kinds of imaging combination was higher than that of their respective ones, and the difference was statistically significant, while the specificity of the three kinds of imaging combination was less than their respective specificity, and the difference was statistically significant. Conclusion: the combination of MRI,~ _ (99m) Tc-MIBI radionuclide imaging and color Doppler ultrasound is of high diagnostic value in the preoperative localization of parathyroid lesions and can effectively assist the surgical treatment of SHPT.
【作者單位】： 北京大學(xué)民航臨床醫(yī)學(xué)院民航總醫(yī)院耳鼻咽喉頭頸外科;
【分類號】：R582.1

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