發(fā)布時間：2019-07-03 10:40

【摘要】：目的 觀察拜唐蘋中餐時頓服對使用優(yōu)泌樂25早、晚餐前注射的中餐后血糖控制不佳的2型糖尿病患者的療效。方法 選取優(yōu)泌樂25早、晚餐前皮下注射,早、晚餐前血糖基本控制,但中餐后2 h血糖控制不佳(10 mmol/L)的2型糖尿病患者86例,隨機分為兩組:A組維持早、晚胰島素劑量不變,中餐時增加拜唐蘋1次頓服,50~100 mg;B組維持早、晚胰島素劑量不變,中餐前增加1次優(yōu)泌樂25(0.1~0.3 u/kg體重)。2周后比較7∶00血糖譜(3餐前、3餐后2 h、睡前)變化及低血糖發(fā)生頻率。結果 (1)兩組中餐后2 h血糖達標率比較:A組為86.05%,B組為88.37%,兩組比較,差異無統(tǒng)計學意義(P0.05);(2)兩組7∶00血糖值比較:A組晚餐后2 h血糖(7.8±1.0)mmol/L,B組(6.1±1.1)mmol/L,兩組比較,差異有統(tǒng)計學意義(P0.05),兩組3餐前、早餐后2 h、中餐后2 h、睡前血糖比較,差異無統(tǒng)計學意義;(3)低血糖反應:A組為4.65%,B組為18.60%,兩組比較,差異有統(tǒng)計學意義(P0.05)。結論 采用優(yōu)泌樂25早、晚餐前皮下注射的中餐后2 h血糖控制不佳者,中餐時增加拜唐蘋1次頓服與中餐前增加1次優(yōu)泌樂25注射,控制血糖療效相當,低血糖風險減少。
[Abstract]:Objective to observe the effect of Baitang apple Chinese meal on type 2 diabetes mellitus patients with type 2 diabetes mellitus who were treated with Youbile 25 morning and poor postmeal blood glucose control before dinner. Methods 86 patients with type 2 diabetes mellitus whose blood glucose was basically controlled before dinner, subcutaneous injection before dinner, early and pre-dinner, but poor blood glucose control at 2 hours after Chinese meal (10 mmol/L), were randomly divided into two groups: group A maintained early and late insulin dose, and increased the dose of BaiTangping once at Chinese meal, 50 鈮，

本文編號：2509322