【摘要】：目的探討新疆維吾爾族老年男性代謝綜合征(metabolic syndrome,MS)與骨密度(bone mineral density,BMD)的相關(guān)性。方法采用雙能X線吸收測定法檢測366例[分為MS組(236例)和非MS組(130例)]新疆維吾爾族老年男性的骨密度,通過全自動(dòng)生化分析儀檢測空腹血糖(fasting blood glucose,FBG)、總膽固醇(total cholesterol,TC)、甘油三酯(triglyceride,TG)、高密度脂蛋白膽固醇(high density lipoprotein cholesterol,HDL-C)、低密度脂蛋白膽固醇(low density lipoprotein cholesterol,LDL-C)、血鈣(Ca)、25羥維生素D[25(OH)D]、血清總睪酮(T)、血紅蛋白(Hb),測量血壓[血管收縮壓(systolic blood pressure,SBP)和血管舒張壓(diastolic blood pressure,DBP)],測量身高、體重,計(jì)算體質(zhì)量指數(shù)(body mass index,BMI)。結(jié)果新疆維吾爾族老年男性MS患者骨質(zhì)疏松檢出率高于非MS組,MS組與非MS組間年齡、BMI、FBG、HDL-C、SBP、DBP組間差異有統(tǒng)計(jì)學(xué)意義(P0.05)。無論是否為MS患者,骨質(zhì)疏松患者Hb、TC、HDL-C均低于非骨質(zhì)疏松患者(P0.05)。MS組中骨質(zhì)疏松患者BMI低于非骨質(zhì)疏松患者,非MS組中非骨質(zhì)疏松患者25(OH)D高于骨質(zhì)疏松患者(P0.05)。骨密度與HDL-C的水平呈負(fù)相關(guān)(標(biāo)化B=-0.538,P=0.003),與BMI呈正相關(guān)(標(biāo)化B=0.054,P=0.002),與Hb呈正相關(guān)(標(biāo)化B=0.022,P=0.000)。結(jié)論新疆維吾爾族老年男性代謝綜合征患者發(fā)生骨質(zhì)疏松的風(fēng)險(xiǎn)取決于各影響因素間的平衡。
[Abstract]:Objective to investigate the relationship between metabolic syndrome (metabolic syndrome,MS) and bone mineral density (bone mineral density,BMD) in elderly men of Uygur nationality in Xinjiang. Methods Bone mineral density (bone mineral density), fasting blood glucose (fasting blood glucose,FBG), total cholesterol (total cholesterol,TC), glycerol (triglyceride,TG), high density lipoprotein cholesterol (high density lipoprotein cholesterol,HDL-C) and low density lipoprotein cholesterol (low density lipoprotein cholesterol,) were measured by dual energy X-ray absorptiometry in 366 elderly men [divided into MS group (n = 236) and non-MS group (n = 130)]. Fasting blood glucose (fasting blood glucose,FBG), total cholesterol (triglyceride,TG), high density lipoprotein cholesterol (high density lipoprotein cholesterol,HDL-C) and low density lipoprotein cholesterol (LDL) were measured by automatic biochemical analyzer. LDL-C), serum calcium (Ca), 25 hydroxyvitamin D [25 (OH) D], serum total testosterone (T), hemoglobin (Hb), measured blood pressure [systolic blood pressure (systolic blood pressure,SBP) and diastolic blood pressure (diastolic blood pressure,DBP)], height, weight and body mass index (body mass index,BMI) were measured. Results the detection rate of osteoporosis in elderly men with MS in Xinjiang Uygur nationality was higher than that in non-MS group. There were significant differences in age and BMI,FBG,HDL-C,SBP,DBP between MS group and non-MS group (P 0.05). Whether it was MS or not, the Hb,TC,HDL-C of osteoporotic patients was lower than that of non-osteoporotic patients (P 0.05). The BMI of osteoporotic patients in). MS group was lower than that of non-osteoporotic patients, and the 25 (OH) D of non-osteoporotic patients in non-MS group was higher than that of osteoporotic patients (P 0.05). Bone mineral density was negatively correlated with the level of HDL-C (standardized B 鈮，

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