【摘要】：目的:探討老年性哮喘患者在支氣管舒張試驗前后氣道阻力的變化規(guī)律及年齡因素對氣道阻力變化程度的影響。方法:選取臨床上明確診斷為支氣管哮喘的成人患者共50例,根據(jù)年齡分為兩組,(≥60歲老年組為29例,18~60歲對照組為21例),在舒張試驗前后分別進行最大呼氣流速容積曲線(MEFV)測定和脈沖震蕩(IOS)肺功能測定。比較兩組患者各測定指標差異,并對兩種方法測量結(jié)果的相關(guān)性進行分析。結(jié)果:各測定指標在支氣管舒張試驗后較前均獲得明顯改善(P0.05)。研究組與對照組比較,各組指標在舒張試驗前后的改善量均無明顯統(tǒng)計學(xué)差異(P0.05)。IOS中反映氣道阻力的各指標都與FEV1%預(yù)計值有很好的相關(guān)性,其中以X5%相關(guān)程度最高。結(jié)論:老年性哮喘患者在舒張試驗后氣道阻力明顯改善。IOS在測定老年性哮喘氣道阻力中具有重要應(yīng)用價值。
[Abstract]:Objective: to investigate the changes of airway resistance before and after bronchodilation test and the influence of age on airway resistance in senile asthma patients. Methods: a total of 50 adult patients with bronchial asthma were selected and divided into two groups according to their age (29 cases in the elderly group 鈮，

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