【摘要】：目的探討糖尿病(DM)并發(fā)醫(yī)院感染患者的病原菌分布及危險因素。方法選擇醫(yī)院2015年9月-2017年2月685例糖尿病患者,分析感染患者的感染率、病原菌分布、藥敏特征及感染相關(guān)危險因素。結(jié)果 685例糖尿病患者共發(fā)生醫(yī)院感染134例,感染率19.56%。感染以呼吸系統(tǒng)、泌尿系統(tǒng)感染為主。共分離174株病原菌,其中,革蘭陰性菌102株占58.62%,革蘭陽性菌70株占40.23%,真菌2株占1.15%。藥敏結(jié)果顯示,銅綠假單胞菌對亞胺培南敏感率最高為100.00%,對慶大霉素敏感率最低為52.63%。肺炎克雷伯菌對哌拉西林敏感率最高為100.00%,對慶大霉素敏感率最低為54.17%。大腸埃希菌對亞胺培南敏感率最高為95.00%,對氨芐西林敏感率最低為35.00%。金黃色葡萄球菌對苯唑西林敏感率最高為96.15%,對左氧氟沙星敏感率最低為30.77%。糞腸球菌對苯唑西林敏感率最高為100.00%,對青霉素敏感率最低為27.78%。溶血葡萄球菌對萬古霉素敏感率最高為100.00%,對青霉素敏感率最低為21.43%。年齡≥60歲、住院時間≥20天、糖化血紅蛋白≥9.0%、有侵入性操作、住院前15d內(nèi)抗菌藥物應(yīng)用是DM并發(fā)醫(yī)院感染的獨立危險因素(P0.05)。結(jié)論針對糖尿病并發(fā)醫(yī)院感染的高危因素,加強(qiáng)防控措施以降低感染率。
[Abstract]:Objective to investigate the distribution and risk factors of pathogenic bacteria in patients with diabetic (DM) complicated with nosocomial infection. Methods from September 2015 to February 2017, 685 patients with diabetes mellitus were selected. The infection rate, distribution of pathogenic bacteria, drug sensitivity and risk factors were analyzed. Results there were 134 cases of nosocomial infection in 685 patients with diabetes mellitus, the infection rate was 19.56%. The infection is mainly respiratory system and urinary system infection. A total of 174 strains of pathogenic bacteria were isolated, of which 102 were Gram-negative bacteria (58.62%), 70 Gram-positive bacteria (40.23%) and 2 fungi (1.15%). The susceptibility rate of Pseudomonas aeruginosa to imipenem was 100.00% and that to gentamicin was 52.63%. The susceptibility rate of Klebsiella pneumoniae to piperacillin and gentamicin was 100.00% and 54.17% respectively. The highest susceptibility rate of Escherichia coli to imipenem was 95.00%, and the lowest to ampicillin was 35.00%. The highest susceptibility rate of Staphylococcus aureus to oxacillin was 96.15%, and the lowest to levofloxacin was 30.77%. The highest susceptibility rate of Enterococcus faecalis to oxacillin was 100.00%, and the lowest to penicillin was 27.78%. The highest susceptibility rate of Staphylococcus hemolyticus to vancomycin was 100.00%, and the lowest to penicillin was 21.43%. The age 鈮，

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