【摘要】：篩選急性重度有機(jī)磷中毒患者195例,根據(jù)氯解磷定用藥方案不同分成持續(xù)靜滴治療組和沖擊治療組,比較2組患者治療情況。結(jié)果顯示,與持續(xù)靜滴治療組比較,沖擊治療組死亡率顯著增高;機(jī)械通氣比例和入院4 h后新增機(jī)械通氣比例均顯著升高、機(jī)械通氣時間顯著延長(P0.05);持續(xù)靜滴治療組較沖擊治療組阿托品用量顯著減少(P0.05);而氯解磷定用量及膽堿酯酶活性動態(tài)變化2組比較無統(tǒng)計學(xué)差異(P0.05)。持續(xù)靜滴治療組療效明顯優(yōu)于沖擊治療組。
[Abstract]:195 patients with acute severe organophosphorus poisoning were selected and divided into continuous intravenous drip group and impulse therapy group. The results showed that compared with the continuous intravenous drip group, the mortality rate of the shock treatment group was significantly higher, the ratio of mechanical ventilation and the proportion of new mechanical ventilation were significantly increased, and the mechanical ventilation time was significantly prolonged (P0.05). The dosage of atropine in the continuous intravenous drip group was significantly lower than that in the impact treatment group (P0.05), while there was no significant difference between the two groups in the dosage of chlorophosphoridine and the dynamic change of cholinesterase activity (P0.05). The curative effect of continuous intravenous drip group was better than that of impact therapy group.
【作者單位】： 中國醫(yī)科大學(xué)附屬第一醫(yī)院急診科;
【分類號】：R595.4

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