代謝綜合征人群中醫(yī)體質(zhì)調(diào)查及個體化調(diào)養(yǎng)保健方案的療效
發(fā)布時間：2018-10-29 10:26
【摘要】：目的對代謝綜合征患者進行中醫(yī)體質(zhì)辨識,根據(jù)患者不同中醫(yī)體質(zhì)制定個體化調(diào)養(yǎng)保健方案進行干預(yù)并評價其療效。方法在401醫(yī)院體檢中心進行體檢的人群中,按納入標準和排除標準選擇代謝綜合征患者共280例作為研究對象,為每位代謝綜合征患者檢測代謝綜合征的西醫(yī)指標包括體重指數(shù)、血壓、空腹狀態(tài)下的血甘油三酯、高密度脂蛋白膽固醇和血糖水平,并進行中醫(yī)體質(zhì)評定。將280例代謝綜合征患者隨機分為對照組和干預(yù)組,每組各140例患者。對照組患者根據(jù)各項指南用藥原則合理服用降壓、降糖、降脂藥,不實施其他干預(yù)。干預(yù)組患者在根據(jù)各項指南用藥原則合理服用降壓、降糖、降脂藥的基礎(chǔ)上,根據(jù)每位患者的不同體質(zhì)選擇適合其體質(zhì)的個體化調(diào)養(yǎng)保健方案,包括指導(dǎo)科學(xué)合理的飲食、行為引導(dǎo)、精神調(diào)攝、心理疏導(dǎo)、體育運動、環(huán)境起居、生活習(xí)慣和生活方式的干預(yù)、保健穴位、中藥調(diào)理等多項綜合性的保健指導(dǎo)。干預(yù)治療6個月后,觀察兩組患者體重指數(shù)、血壓、空腹狀態(tài)下的血甘油三酯、高密度脂蛋白膽固醇和血糖水平的變化,以評價個體化調(diào)養(yǎng)保健方案的效果。結(jié)果280例代謝綜合征患者經(jīng)中醫(yī)體質(zhì)量表辨識,體質(zhì)分布特征如下:痰濕質(zhì)79例,氣虛質(zhì)66例,濕熱質(zhì)48例,陰虛質(zhì)32例,血瘀質(zhì)18例,陽虛質(zhì)15例,氣郁質(zhì)11例,平和質(zhì)9例,特稟質(zhì)2例。兩組患者治療前的年齡、性別、體質(zhì)類型無統(tǒng)計學(xué)差異(P0.05),兩組患者治療前的體重指數(shù)、血壓、空腹狀態(tài)下的血甘油三酯、高密度脂蛋白膽固醇和血糖水平無統(tǒng)計學(xué)差異(P0.05)。兩組患者分別采用不同治療方案進行干預(yù),在干預(yù)6個月后,復(fù)查結(jié)果顯示,與本組患者治療前相比較,兩組患者治療后的體重指數(shù)、血壓和血甘油三酯水平均降低(P0.05),血高密度脂蛋白膽固醇水平增高(P0.05)。干預(yù)組患者的空腹血糖水平較治療前降低(P0.05),而對照組患者的空腹血糖水平較治療前未見明顯改變(P0.05)。兩組患者的治療結(jié)果組間比較顯示,干預(yù)組患者治療前、后的體重指數(shù)、血壓、空腹狀態(tài)下的血甘油三酯、高密度脂蛋白膽固醇和血糖水平各項指標變化情況均較對照組更顯著(P0.05)。結(jié)論對該研究中的280例代謝綜合征患者進行中醫(yī)體質(zhì)辨識,主要體質(zhì)類型依次為痰濕質(zhì)、氣虛質(zhì)、濕熱質(zhì),其中以痰濕體質(zhì)所占比例最多。本研究中對干預(yù)組患者實施針對不同體質(zhì)的個體化調(diào)養(yǎng)保健方案,結(jié)合各項指南指導(dǎo)服用西醫(yī)藥物治療,而對照組僅在各項指南指導(dǎo)下服用西醫(yī)藥物治療。兩組患者分別治療6個月后,干預(yù)組患者的體重指數(shù)、血壓、空腹狀態(tài)下的血甘油三酯、高密度脂蛋白膽固醇和血糖各項指標的均較對照組改善更顯著,說明根據(jù)不同中醫(yī)體質(zhì)類型制定的個體化調(diào)養(yǎng)保健方案對代謝綜合征的治療切實有效。這體現(xiàn)了中西醫(yī)結(jié)合的治療特色和優(yōu)勢。
[Abstract]:Objective to identify the physique of the patients with metabolic syndrome (MS), and to make the individual health care program according to the different constitution of TCM and evaluate the curative effect. Methods A total of 280 patients with metabolic syndrome were selected according to inclusion criteria and exclusion criteria. Western medicine indexes including body mass index (BMI) were measured for each patient with metabolic syndrome. Blood pressure, fasting serum triglyceride, high density lipoprotein cholesterol and blood glucose levels, and Chinese medicine constitution evaluation. 280 patients with metabolic syndrome were randomly divided into control group and intervention group with 140 patients in each group. The patients in the control group took antihypertensive, hypoglycemic and lipid-lowering drugs according to the guidelines. On the basis of rational taking of antihypertensive, hypoglycemic and lipid-lowering drugs in accordance with the principles of drug use in the intervention group, the patients in the intervention group selected individual health care programs suitable for their physique according to the different physique of each patient, including guiding a scientific and reasonable diet. Behavioral guidance, mental adjustment, psychological guidance, sports, environmental living, living habits and lifestyle intervention, health care acupoints, traditional Chinese medicine, and other comprehensive health care guidance. After 6 months of intervention, the changes of body mass index, blood pressure, serum triglyceride, high density lipoprotein cholesterol and blood glucose were observed in order to evaluate the effect of individualized regimen. Results the physical distribution characteristics of 280 patients with metabolic syndrome were as follows: phlegm dampness 79 cases, qi deficiency 66 cases, dampness and heat 48 cases, yin deficiency 32 cases, blood stasis 18 cases, yang deficiency 15 cases, qi stagnation 11 cases. There were 9 cases of pacification and 2 cases of special nature. There was no significant difference in age, sex and physical type between the two groups before treatment (P0.05). The body mass index (BMI), blood pressure (BP), triglyceride (triglyceride) in fasting state were not significantly different between the two groups before treatment (P0.05). There was no significant difference in high density lipoprotein cholesterol and blood glucose levels (P0.05). After 6 months of intervention, the results showed that the body mass index (BMI) of the two groups was higher than that of the patients before treatment. Blood pressure and serum triglyceride level were decreased (P0.05), blood high density lipoprotein cholesterol level increased (P0.05). The fasting blood glucose level in the intervention group was lower than that before treatment (P0.05), while the fasting blood glucose level in the control group was not significantly changed compared with that before treatment (P0.05). A comparison between the two groups showed that the body mass index (BMI), blood pressure (BP), serum triglyceride (TG) in fasting state were measured before and after treatment in the intervention group. The changes of high density lipoprotein cholesterol and blood glucose levels were more significant than those of the control group (P0.05). Conclusion 280 cases of metabolic syndrome in this study were identified by TCM physique. The main physique types were phlegm dampness, qi deficiency, dampness and heat, among which phlegm and dampness constitution accounted for the most. In this study, the patients in the intervention group were given individualized health care program for different physique, combined with the guidelines to guide the treatment of western medicine, while the control group only took western medicine under the guidance of various guidelines. After 6 months of treatment, the body mass index, blood pressure, serum triglyceride, high density lipoprotein cholesterol and blood glucose in the intervention group were significantly improved than those in the control group. The results showed that the individualized regimen was effective in the treatment of metabolic syndrome according to different physique types of traditional Chinese medicine. This reflects the treatment characteristics and advantages of integrated Chinese and western medicine.
【學(xué)位授予單位】：青島大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2015
【分類號】：R589
本文編號：2297431
[Abstract]:Objective to identify the physique of the patients with metabolic syndrome (MS), and to make the individual health care program according to the different constitution of TCM and evaluate the curative effect. Methods A total of 280 patients with metabolic syndrome were selected according to inclusion criteria and exclusion criteria. Western medicine indexes including body mass index (BMI) were measured for each patient with metabolic syndrome. Blood pressure, fasting serum triglyceride, high density lipoprotein cholesterol and blood glucose levels, and Chinese medicine constitution evaluation. 280 patients with metabolic syndrome were randomly divided into control group and intervention group with 140 patients in each group. The patients in the control group took antihypertensive, hypoglycemic and lipid-lowering drugs according to the guidelines. On the basis of rational taking of antihypertensive, hypoglycemic and lipid-lowering drugs in accordance with the principles of drug use in the intervention group, the patients in the intervention group selected individual health care programs suitable for their physique according to the different physique of each patient, including guiding a scientific and reasonable diet. Behavioral guidance, mental adjustment, psychological guidance, sports, environmental living, living habits and lifestyle intervention, health care acupoints, traditional Chinese medicine, and other comprehensive health care guidance. After 6 months of intervention, the changes of body mass index, blood pressure, serum triglyceride, high density lipoprotein cholesterol and blood glucose were observed in order to evaluate the effect of individualized regimen. Results the physical distribution characteristics of 280 patients with metabolic syndrome were as follows: phlegm dampness 79 cases, qi deficiency 66 cases, dampness and heat 48 cases, yin deficiency 32 cases, blood stasis 18 cases, yang deficiency 15 cases, qi stagnation 11 cases. There were 9 cases of pacification and 2 cases of special nature. There was no significant difference in age, sex and physical type between the two groups before treatment (P0.05). The body mass index (BMI), blood pressure (BP), triglyceride (triglyceride) in fasting state were not significantly different between the two groups before treatment (P0.05). There was no significant difference in high density lipoprotein cholesterol and blood glucose levels (P0.05). After 6 months of intervention, the results showed that the body mass index (BMI) of the two groups was higher than that of the patients before treatment. Blood pressure and serum triglyceride level were decreased (P0.05), blood high density lipoprotein cholesterol level increased (P0.05). The fasting blood glucose level in the intervention group was lower than that before treatment (P0.05), while the fasting blood glucose level in the control group was not significantly changed compared with that before treatment (P0.05). A comparison between the two groups showed that the body mass index (BMI), blood pressure (BP), serum triglyceride (TG) in fasting state were measured before and after treatment in the intervention group. The changes of high density lipoprotein cholesterol and blood glucose levels were more significant than those of the control group (P0.05). Conclusion 280 cases of metabolic syndrome in this study were identified by TCM physique. The main physique types were phlegm dampness, qi deficiency, dampness and heat, among which phlegm and dampness constitution accounted for the most. In this study, the patients in the intervention group were given individualized health care program for different physique, combined with the guidelines to guide the treatment of western medicine, while the control group only took western medicine under the guidance of various guidelines. After 6 months of treatment, the body mass index, blood pressure, serum triglyceride, high density lipoprotein cholesterol and blood glucose in the intervention group were significantly improved than those in the control group. The results showed that the individualized regimen was effective in the treatment of metabolic syndrome according to different physique types of traditional Chinese medicine. This reflects the treatment characteristics and advantages of integrated Chinese and western medicine.
【學(xué)位授予單位】：青島大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2015
【分類號】：R589
【參考文獻】
相關(guān)期刊論文 前1條
1 潘玲,馮全生;八味丸方藥對代謝綜合征患者治療效應(yīng)的臨床觀察[J];四川生理科學(xué)雜志;2005年02期
，本文編號：2297431
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