【摘要】：目的:評價(jià)肥胖成人安靜及運(yùn)動(dòng)狀態(tài)下心臟結(jié)構(gòu)和功能的特點(diǎn),旨在評估心臟改變的風(fēng)險(xiǎn)性和不良后果。方法:選取130名40~60歲的北京市居民(男n=29,女n=101),依照BMI分類標(biāo)準(zhǔn),分成體重正常組(n=57)、超重組(n=56)、肥胖組(n=17)。每名受試者蹬騎臥式功率車進(jìn)行起始25 W,每2 min遞增25 W的運(yùn)動(dòng),每等級運(yùn)動(dòng)結(jié)束前30 s及恢復(fù)期測定超聲心動(dòng)圖。結(jié)果:1)與體重正常組相比,肥胖組舒張末期室間隔厚度(IVSd)、左心室舒張末期內(nèi)徑(LVIDd)、舒張末期左室后壁厚度(LVPWd)、左心室舒張末期容積(EDV)、左心室質(zhì)量(LVM)、左心室質(zhì)量指數(shù)(LVMI)、心率(HR)、每搏量(SV)、心輸出量(CO)均非常顯著性增加(P0.01)。2)肥胖成人發(fā)生左心室肥厚的比例遠(yuǎn)高于體重正常者和超重者。3)運(yùn)動(dòng)過程中肥胖者CO、SV非常顯著性高于體重正常組(P0.01),EF、HR無顯著性差異(P0.05)。結(jié)論:超重可引起心臟肥大,左室收縮功能異常,并隨超重向肥胖過渡而加重。肥胖者運(yùn)動(dòng)中每搏量、心輸出量較高,但心功能儲(chǔ)備低于體重正常者,且運(yùn)動(dòng)后心率恢復(fù)受損。肥胖者安靜及運(yùn)動(dòng)狀態(tài)下心臟功能異常增強(qiáng)的原因尚需進(jìn)一步深入研究。
[Abstract]:Objective: to evaluate the characteristics of cardiac structure and function in obese adults under quiet and exercise conditions, and to evaluate the risk and adverse consequences of cardiac changes. Methods: 130 Beijing residents aged 40 to 60 years (male nong 29, female nong 101) were divided into normal weight group (n = 57), superrecombinant group (n = 56) and obese group (n = 17) according to BMI classification criteria. Each participant was used for 25 wattage, 25 W for every 2 min, 30 seconds before the end of each grade of exercise, and 30 seconds before the end of each grade of exercise, and the echocardiography was measured during the convalescence period. Results: 1) compared with the normal weight group, Obesity group end diastolic septal thickness (IVSd), left ventricular end diastolic diameter (LVIDd), end diastolic left ventricular posterior wall thickness (LVPWd), left ventricular end diastolic volume (EDV), left ventricular mass (LVM), left ventricular mass index (LVMI), heart rate (HR), (SV), cardiac output (CO) The incidence of left ventricular hypertrophy in obese adults was significantly higher than that in normal and overweight subjects (P0.01). The CO,SV of obese subjects during exercise was significantly higher than that of normal subjects (P0.01). There was no significant difference between obese adults and obese adults during exercise (P0.05). Conclusion: overweight may lead to cardiac hypertrophy, abnormal left ventricular systolic function and increase with the transition from overweight to obesity. The cardiac output per stroke volume was higher in obese subjects, but the cardiac function reserve was lower than that of normal body weight, and the heart rate was impaired after exercise. The causes of abnormal enhancement of cardiac function in obese patients during quiet and exercise need further study.
【作者單位】： 北京體育大學(xué)運(yùn)動(dòng)與體質(zhì)健康教育部重點(diǎn)實(shí)驗(yàn)室;
【基金】：“十二五”國家科技支撐計(jì)劃課題資助項(xiàng)目(2012BAK21B01)
【分類號】：R589.2

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