【摘要】：正肥胖與糖尿病(DM)關(guān)系密切,是2型DM(T2DM)的危險因素之一。多數(shù)T2DM患者體型肥胖或超重,流行病學研究表明,在T2DM自然病程早期,肥胖者常表現(xiàn)有胰島素抵抗(IR)和糖調(diào)節(jié)受損。減輕體重有助于控制血糖、降低DM并發(fā)癥發(fā)生率和死亡率~([1])。肥胖的T2DM患者在選擇降糖藥物時,不僅要能有效地降糖,且應不增加體重甚至降低體重~([2])。本文綜述能幫助患者維持合理體質(zhì)量的降糖藥物。
[Abstract]:Positive obesity is closely associated with diabetes mellitus (DM) and is one of the risk factors of type 2 DM (T2DM). Most T2DM patients are obese or overweight. Epidemiological studies show that the obese patients often exhibit insulin resistance, (IR) and impaired glucose regulation in the early stage of T2DM. Weight loss helps to control blood sugar, reduce the incidence of DM complications and mortality. Obese T2DM patients should not only be able to reduce glucose effectively, but also not gain weight or even lose weight when choosing hypoglycemic drugs. This article reviews hypoglycemic drugs that can help patients maintain reasonable body mass.
【作者單位】： 淄博市中心醫(yī)院藥學部;
【分類號】：R587.1;R589.2

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