以發(fā)熱肌酸激酶升高為首發(fā)表現(xiàn)的免疫介導(dǎo)性壞死性肌病1例
發(fā)布時(shí)間:2018-08-19 11:44
【摘要】:正他汀類藥物是治療心血管疾病常用藥物之一,能夠顯著降低低密度脂蛋白水平[1]。隨著他汀類藥物在臨床上的廣泛應(yīng)用,其常見不良反應(yīng)也已廣為認(rèn)識,但尚需提高對少見不良反應(yīng)的認(rèn)識[2]。本文收治1例以發(fā)熱、橫紋肌溶解為首發(fā)表現(xiàn),病理證實(shí)為免疫介導(dǎo)壞死性肌病,排除其他原因,診斷為瑞舒伐他汀(rosuvastatin)所致肌溶解,現(xiàn)報(bào)道如下,以期望能夠提高臨床醫(yī)生對藥物相關(guān)不良反應(yīng)的認(rèn)識,
[Abstract]:Orthostatin is one of the commonly used drugs in the treatment of cardiovascular disease, which can significantly reduce the low density lipoprotein level [1]. With the wide use of statins in clinical practice, its common adverse reactions have been widely recognized, but it is necessary to improve the understanding of rare adverse reactions [2]. A case with fever, rhabdomyolysis as the first manifestation, immuno-mediated necrotic myopathy confirmed by pathology, excluding other causes, was diagnosed as myolysis caused by recuvastatin (rosuvastatin). The present report is as follows. In the hope of raising clinicians' awareness of drug-related adverse reactions,
【作者單位】: 北京大學(xué)第一醫(yī)院感染疾病科;北京大學(xué)第一醫(yī)院神經(jīng)內(nèi)科;
【分類號】:R593.2
[Abstract]:Orthostatin is one of the commonly used drugs in the treatment of cardiovascular disease, which can significantly reduce the low density lipoprotein level [1]. With the wide use of statins in clinical practice, its common adverse reactions have been widely recognized, but it is necessary to improve the understanding of rare adverse reactions [2]. A case with fever, rhabdomyolysis as the first manifestation, immuno-mediated necrotic myopathy confirmed by pathology, excluding other causes, was diagnosed as myolysis caused by recuvastatin (rosuvastatin). The present report is as follows. In the hope of raising clinicians' awareness of drug-related adverse reactions,
【作者單位】: 北京大學(xué)第一醫(yī)院感染疾病科;北京大學(xué)第一醫(yī)院神經(jīng)內(nèi)科;
【分類號】:R593.2
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