【摘要】：目的探討碘超足量地區(qū)中、老年人群不同吸煙狀態(tài)與甲狀腺的關(guān)系及其他相關(guān)影響因素。方法于2011年隨機抽取貴陽市40~80歲常駐居民共10 140例,進行問卷調(diào)查、體格、生化及甲狀腺B超檢查。應(yīng)用回歸分析比較不同吸煙狀態(tài)與甲狀腺體積、促甲狀腺素(TSH)、甲狀腺腫和甲狀腺結(jié)節(jié)之間的關(guān)系及其他相關(guān)因素。結(jié)果經(jīng)排除,共納入研究對象6 122例;經(jīng)分析,曾經(jīng)吸煙、目前吸煙及男性與TSH呈負相關(guān)(P0.05);目前吸煙、男性、體質(zhì)量指數(shù)與甲狀腺體積呈正相關(guān)(P0.05);吸煙與甲狀腺腫、甲狀腺結(jié)節(jié)的患病率均無關(guān)(P0.05),年齡、女性是甲狀腺結(jié)節(jié)的危險因素(P0.05)。結(jié)論吸煙可影響促甲狀腺素水平,目前吸煙者有著較大的甲狀腺體積,吸煙與甲狀腺腫、甲狀腺結(jié)節(jié)的患病率均無關(guān)。
[Abstract]:Objective to investigate the relationship between different smoking status and thyroid gland and other related factors in iodine excess population. Methods A total of 10 140 resident residents aged 4080 in Guiyang City were randomly selected in 2011 and investigated with questionnaire, physique, biochemistry and thyroid B ultrasonic examination. Regression analysis was used to compare the relationship between smoking status and thyroid volume, thyrotropin (TSH), goiter and thyroid nodules and other related factors. Results A total of 6,122 subjects were included in the study. After analysis, there was a negative correlation between smoking and TSH (P0.05), a positive correlation between body mass index (BMI) and thyroid volume (P0.05), smoking and goiter (P0.05). The prevalence of thyroid nodule was not significant (P0.05), age and female were the risk factors of thyroid nodule (P0.05). Conclusion smoking can affect the level of thyrotropin. At present, smokers have a large thyroid volume, smoking has no relationship with goiter and thyroid nodule prevalence.
【作者單位】： 貴州醫(yī)科大學(xué)附屬醫(yī)院內(nèi)分泌代謝病科;
【基金】：貴州省科技合作計劃項目(黔科合LH[2015]7413號) 貴州省省長資金臨床應(yīng)用課題專項研究(黔省專合字2012-100號)
【分類號】：R581.9

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