發(fā)布時間：2018-08-04 21:18

【摘要】：目的:探討2型糖尿病(type 2 diabetes mellitus,T2DM)患者血清中性粒細(xì)胞與淋巴細(xì)胞比值(serum neutrophil-lymphocyte ratio,NLR)與大血管病變的相關(guān)性。方法:將211例T2DM患者分為單純T2DM(T)組、合并下肢動脈粥樣硬化(L)組、合并頸部動脈粥樣硬化(C)組、合并下肢動脈兼頸部動脈粥樣硬化(LC)組。收集患者的一般臨床指標(biāo)及生化指標(biāo)。結(jié)果:單因素方差分析及LSD多重比較分析顯示,L組、C組、LC組的NLR均數(shù)均大于T組(P0.05);Logistic多元回歸分析結(jié)果顯示,年齡、舒張壓、低密度脂蛋白膽固醇、NLR是2型糖尿病大血管病變的危險因素(P0.05)。結(jié)論:NLR與2型糖尿病大血管病變存在相關(guān)性。
[Abstract]:Objective: to investigate the relationship between serum neutrophil-lymphocyte neutrophil / lymphocyte ratio and macroangiopathy in patients with type 2 diabetes mellitus (type 2 diabetes mellitusus T2DM). Methods: two hundred and eleven patients with T2DM were divided into T2DM (T) group, (L) group, (C) group and (LC) group. General clinical and biochemical indexes were collected. Results: univariate ANOVA and LSD multiple comparison analysis showed that the mean of NLR in group C was higher than that in group T (P0.05). The results of multiple logistic regression analysis showed that age, diastolic blood pressure, and diastolic blood pressure were significantly higher in group C than in group T (P0.05). Low density lipoprotein cholesterol (LDL-C) NLR was a risk factor for type 2 diabetic macroangiopathy (P0.05). Conclusion there is a correlation between the ratio of 1: NLR and type 2 diabetic macroangiopathy.
【作者單位】： 延安大學(xué)附屬醫(yī)院內(nèi)分泌科;西安醫(yī)學(xué)院第一附屬醫(yī)院內(nèi)分泌科;
【基金】：延安大學(xué)研究生教育創(chuàng)新資助項目
【分類號】：R587.2
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本文編號：2165180